User profiles for Erick Moen

Erick Moen

California Institute of Technology
Verified email at caltech.edu
Cited by 1750

Deep learning for cellular image analysis

E Moen, D Bannon, T Kudo, W Graf, M Covert… - Nature …, 2019 - nature.com
Recent advances in computer vision and machine learning underpin a collection of
algorithms with an impressive ability to decipher the content of images. These deep learning …

Accurate cell tracking and lineage construction in live-cell imaging experiments with deep learning

E Moen, E Borba, G Miller, M Schwartz, D Bannon… - Biorxiv, 2019 - biorxiv.org
Live-cell imaging experiments have opened an exciting window into the behavior of living
systems. While these experiments can produce rich data, the computational analysis of these …

Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning

NF Greenwald, G Miller, E Moen, A Kong, A Kagel… - Nature …, 2022 - nature.com
A principal challenge in the analysis of tissue imaging data is cell segmentation—the task of
identifying the precise boundary of every cell in an image. To address this problem we …

DeepCell 2.0: Automated cloud deployment of deep learning models for large-scale cellular image analysis

D Bannon, E Moen, E Borba, A Ho… - …, 2018 - authors.library.caltech.edu
Deep learning is transforming the ability of life scientists to extract information from images.
While these techniques have superior accuracy in comparison to conventional approaches …

[HTML][HTML] Quantifying pulsed electric field-induced membrane nanoporation in single cells

EK Moen, BL Ibey, HT Beier, AM Armani - Biochimica et Biophysica Acta …, 2016 - Elsevier
Plasma membrane disruption can trigger a host of cellular activities. One commonly observed
type of disruption is pore formation. Molecular dynamic (MD) simulations of simplified lipid …

DeepCell Kiosk: scaling deep learning–enabled cellular image analysis with Kubernetes

D Bannon, E Moen, M Schwartz, E Borba, T Kudo… - Nature …, 2021 - nature.com
Deep learning is transforming the analysis of biological images, but applying these models
to large datasets remains challenging. Here we describe the DeepCell Kiosk, cloud-native …

[HTML][HTML] Asymmetrical bipolar nanosecond electric pulse widths modify bipolar cancellation

CM Valdez, RA Barnes Jr, CC Roth, EK Moen… - Scientific reports, 2017 - nature.com
A bipolar (BP) nanosecond electric pulse (nsEP) exposure generates reduced calcium influx
compared to a unipolar (UP) nsEP. This attenuated physiological response from a BP nsEP …

The interphase interval within a bipolar nanosecond electric pulse modulates bipolar cancellation

CM Valdez, R Barnes Jr, CC Roth, E Moen… - …, 2018 - Wiley Online Library
Nanosecond electric pulse (nsEP) exposure generates an array of physiological effects.
The extent of these effects is impacted by whether the nsEP is a unipolar (UP) or bipolar (BP) …

[PDF][PDF] Detecting subtle plasma membrane perturbation in living cells using second harmonic generation imaging

EK Moen, BL Ibey, HT Beier - Biophysical journal, 2014 - cell.com
The requirement of center asymmetry for the creation of second harmonic generation (SHG)
signals makes it an attractive technique for visualizing changes in interfacial layers such as …

[HTML][HTML] Game-engine-assisted research platform for scientific computing (GEARS) in virtual reality

BK Horton, RK Kalia, E Moen, A Nakano, K Nomura… - SoftwareX, 2019 - Elsevier
The Game-Engine-Assisted Research platform for Scientific computing (GEARS) is a visualization
framework developed at the Materials Genome Innovation for Computational Software …