Background Large efforts have recently been made to automate the sample preparation
protocols for massively parallel sequencing in order to match the increasing instrument …

Because human white adipocytes display a high turnover throughout adulthood, a
continuous supply of precursor cells is required to maintain adipogenesis. Bone marrow (BM)-derived …

Background Whole genome amplification (WGA) is currently a prerequisite for single cell
whole genome or exome sequencing. Depending on the method used the rate of artifact …

High-throughput sequencing platforms mainly produce short-read data, resulting in a loss of
phasing information for many of the genetic variants analysed. For certain applications, it is …

Accurate variant calling and genotyping represent major limiting factors for downstream
applications of single-cell genomics. Here, we report Conbase for the identification of somatic …

The future of human genomics is one that seeks to resolve the entirety of genetic variation
through sequencing. The prospect of utilizing genomics for medical purposes require cost-…

Technologies to study localized host–pathogen interactions are urgently needed. Here, we
present a spatial transcriptomics approach to simultaneously capture host and pathogen …

We present first spring arrival dates of 64 bird species in Råda, Sweden (60 00'N, 13 36'E) for
the period 1938—2004 with almost all species covered more than 50 years. The trend was …

Aim: Lactate dehydrogenase (LDH) increases in several critical conditions that cause cell
damage and could potentially be used for early detection of serious illness in the newborn. Our …

Inhibition of the retinoblastoma tumor suppressor gene (RB) is probably important in the
pathogenesis of urinary bladder cancer. Little information is available concerning allelic loss on …