[HTML][HTML] Imaging of T-cells and their responses during anti-cancer immunotherapy
… Witney, 3 and Erik HJG Aarntzen 2 … Fruhwirth GO, Kneilling M, de Vries IJM, Weigelin B,
Srinivas M, Aarntzen E. The Potential of In vivo Imaging for Optimization of Molecular and …
Srinivas M, Aarntzen E. The Potential of In vivo Imaging for Optimization of Molecular and …
Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients
J Tel, EHJG Aarntzen, T Baba, G Schreibelt… - Cancer research, 2013 - AACR
Vaccination against cancer by using dendritic cells has for more than a decade been based
on dendritic cells generated ex vivo from monocytes or CD34 + progenitors. Here, we report …
on dendritic cells generated ex vivo from monocytes or CD34 + progenitors. Here, we report …
Effective clinical responses in metastatic melanoma patients after vaccination with primary myeloid dendritic cells
Purpose: Thus far, dendritic cell (DC)-based immunotherapy of cancer was primarily based
on in vitro–generated monocyte-derived DCs, which require extensive in vitro manipulation. …
on in vitro–generated monocyte-derived DCs, which require extensive in vitro manipulation. …
Programmed cell death-1/ligand-1 PET imaging: a novel tool to optimize immunotherapy?
…, CML van Herpen, B Piet, EHJG Aarntzen… - PET clinics, 2020 - pet.theclinics.com
Immune checkpoint inhibitors (ICIs) targeting the programmed cell death (ligand)-1 (PD-[L] 1)
axis have emerged at the forefront of cancer treatment. 1 Numerous ICIs have received …
axis have emerged at the forefront of cancer treatment. 1 Numerous ICIs have received …
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients
P Verdijk, EHJG Aarntzen, WJ Lesterhuis… - Clinical Cancer …, 2009 - AACR
Purpose: The success of immunotherapy with dendritic cells (DC) to treat cancer is dependent
on effective migration to the lymph nodes and subsequent activation of antigen-specific T …
on effective migration to the lymph nodes and subsequent activation of antigen-specific T …
Route of administration modulates the induction of dendritic cell vaccine–induced antigen-specific T cells in advanced melanoma patients
…, G Schreibelt, AJA Lambeck, EHJG Aarntzen… - Clinical Cancer …, 2011 - AACR
Purpose: It is unknown whether the route of administration influences dendritic cell (DC)-based
immunotherapy. We compared the effect of intradermal versus intranodal administration …
immunotherapy. We compared the effect of intradermal versus intranodal administration …
Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination
EHJG Aarntzen, IJM De Vries, WJ Lesterhuis… - Cancer research, 2013 - AACR
To evaluate the relevance of directing antigen-specific CD4 + T helper cells as part of effective
anticancer immunotherapy, we investigated the immunologic and clinical responses to …
anticancer immunotherapy, we investigated the immunologic and clinical responses to …
[HTML][HTML] Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 …
ACI Boullart, EHJG Aarntzen, P Verdijk… - Cancer Immunology …, 2008 - Springer
Dendritic cells (DC) are professional antigen-presenting cells of the immune system that play
a key role in regulating T cell-based immunity. In vivo, the capacity of DC to activate T cells …
a key role in regulating T cell-based immunity. In vivo, the capacity of DC to activate T cells …
Improving the Diagnostic Performance of 18F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography in Prosthetic Heart Valve Endocarditis
…, MJ Van Der Vlugt, SAF Streukens, EHJG Aarntzen… - Circulation, 2018 - Am Heart Assoc
Background: 18 F-Fluorodeoxyglucose (FDG) positron-emission tomography/computed
tomography (PET/CT) was recently introduced as a new tool for the diagnosis of prosthetic heart …
tomography (PET/CT) was recently introduced as a new tool for the diagnosis of prosthetic heart …
[HTML][HTML] The Potential of In Vivo Imaging for Optimization of Molecular and Cellular Anti-cancer Immunotherapies
…, B Weigelin, M Srinivas, EHJG Aarntzen - Molecular Imaging and …, 2018 - Springer
This review aims to emphasize the potential of in vivo imaging to optimize current and
upcoming anti-cancer immunotherapies: spanning from preclinical to clinical applications. …
upcoming anti-cancer immunotherapies: spanning from preclinical to clinical applications. …