Copper-and zinc-containing superoxide dismutase, manganese-containing superoxide dismutase, catalase, and glutathione peroxidase in normal and neoplastic …

SL Marklund, NG Westman, E Lundgren, G Roos - Cancer research, 1982 - AACR
Copper- and zinc-containing superoxide dismutase, manganese-containing superoxide
dismutase, catalase, and glutathione peroxidase form the primary enzymic defense against toxic …

A comparative analysis of 23 structures of the amyloidogenic protein transthyretin

A Hörnberg, T Eneqvist, A Olofsson, E Lundgren… - Journal of molecular …, 2000 - Elsevier
Self-assembly of the human plasma protein transthyretin (TTR) into unbranched insoluble
amyloid fibrils occurs as a result of point mutations that destabilize the molecule, leading to …

Upregulation of bcl-2 by the Epstein-Barr virus latent membrane protein LMP1: a B-cell-specific response that is delayed relative to NF-kappa B activation and to …

…, R Hardy, D Croom-Carter, E Lundgren… - Journal of …, 1994 - Am Soc Microbiol
An ability of the Epstein-Barr virus latent membrane protein LMP1 to enhance the survival of
infected B cells through upregulation of the bcl-2 oncogene was first suggested by …

Intracellular calcium oscillations induced in a T‐cell line by a weak 50 Hz magnetic field

…, A Berglund, KH Mild, E Lundgren - Journal of cellular …, 1993 - Wiley Online Library
Applied weak magnetic fields have been shown to affect cellular activity on several levels,
but the mechanisms involved remain elusive. We have decided to study an early signal …

Expression of the Epstein Barr virus transforming protein LMP1 causes a rapid and transient stimulation of the Bcl-2 homologue Mcl-1 levels in B-cell lines

S Wang, M Rowe, E Lundgren - Cancer research, 1996 - AACR
The EBV-encoded latent membrane protein 1 (LMP1) suppresses appoptosis in B lymphocytes
through up-regulation of Bcl-2. However, the maximum induction of Bcl-2 by LMP1 takes …

Antibodies to specific EBNA-1 domains and HLA DRB1⁎ 1501 interact as risk factors for multiple sclerosis

…, M Nyström, K Ruuth, E Lundgren - Journal of …, 2009 - Elsevier
Epitope reactivity of multiple sclerosis (MS) plasma antibodies against the Epstein–Barr virus
protein EBNA-1 and its association with HLA DRB1⁎1501 status was investigated in a case…

One mutation, two distinct disease variants: unravelling the impact of transthyretin amyloid fibril composition

OB Suhr, E Lundgren… - Journal of Internal …, 2017 - Wiley Online Library
Although hereditary transthyretin (h‐ ATTR ) amyloidosis is a monogenetic disease, a large
variation in its phenotype has been observed. The common hypothesis of amyloid fibril …

Only amyloidogenic intermediates of transthyretin induce apoptosis

…, EH Nielsen, SE Svehag, E Lundgren - Biochemical and …, 2002 - Elsevier
In diseases like Alzheimer's disease and familial amyloidotic polyneuropathy (FAP) amyloid
deposits co-localize with areas of neurodegeneration. FAP is associated with mutations of …

Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein

…, MJ Saraiva, E Lundgren… - Proceedings of the …, 2011 - National Acad Sciences
Transthyretin (TTR) is a homotetrameric protein that transports thyroxine and retinol.
Tetramer destabilization and misfolding of the released monomers result in TTR aggregation, …

[HTML][HTML] Probing solvent accessibility of transthyretin amyloid by solution NMR spectroscopy

A Olofsson, JH Ippel, SS Wijmenga, E Lundgren… - Journal of Biological …, 2004 - ASBMB
The human plasma protein transthyretin (TTR) may form fibrillar protein deposits that are
associated with both inherited and idiopathic amyloidosis. The present study utilizes solution …