Single-cell transcriptomic analysis identifies a unique pulmonary lymphangioleiomyomatosis cell
…, M Riccetti, EY Zhang… - American journal of …, 2020 - atsjournals.org
Rationale: Lymphangioleiomyomatosis (LAM) is a metastatic neoplasm of reproductive-age
women associated with mutations in tuberous sclerosis complex genes. LAM causes cystic …
women associated with mutations in tuberous sclerosis complex genes. LAM causes cystic …
Smooth muscle hypertrophy following partial bladder outlet obstruction is associated with overexpression of non-muscle caldesmon
EY Zhang, R Stein, S Chang, Y Zheng… - The American journal of …, 2004 - Elsevier
Partial bladder outlet obstruction (PBOO) induces remodeling of urinary bladder smooth muscle
(detrusor). We demonstrate an increase in bladder wall mass, muscle bundle size, and a …
(detrusor). We demonstrate an increase in bladder wall mass, muscle bundle size, and a …
Activation of choline kinase drives aberrant choline metabolism in esophageal squamous cell carcinomas
W Ma, S Wang, T Zhang, EY Zhang, L Zhou… - … of Pharmaceutical and …, 2018 - Elsevier
Esophageal squamous cell carcinoma (ESCC) is a major health threat worldwide. Research
focused on molecular events associated with ESCC carcinogenesis for diagnosis, treatment …
focused on molecular events associated with ESCC carcinogenesis for diagnosis, treatment …
[HTML][HTML] Rapalog resistance is associated with mesenchymal-type changes in Tsc2-null cells
Tuberous Sclerosis Complex (TSC) and Lymphangioleiomyomatosis (LAM) are caused by
inactivating mutations in TSC1 or TSC2, leading to mTORC1 hyperactivation. The mTORC1 …
inactivating mutations in TSC1 or TSC2, leading to mTORC1 hyperactivation. The mTORC1 …
Rapamycin-resistant poly (ADP-ribose) polymerase-1 overexpression is a potential therapeutic target in lymphangioleiomyomatosis
Y Sun, D Gallacchi, EY Zhang… - American journal of …, 2014 - atsjournals.org
Lymphangioleiomyomatosis (LAM) is a female-predominant cystic lung disease that can
lead to respiratory failure. LAM cells typically have inactivating tuberous sclerosis complex 2 (…
lead to respiratory failure. LAM cells typically have inactivating tuberous sclerosis complex 2 (…
Classification of whole mammogram and tomosynthesis images using deep convolutional neural networks
Mammography is the most popular technology used for the early detection of breast cancer.
Manual classification of mammogram images is a hard task because of the variability of the …
Manual classification of mammogram images is a hard task because of the variability of the …
Whole mammogram image classification with convolutional neural networks
Due to the high variability in tumor morphology and the low signal-to-noise ratio inherent to
mammography, manual classification of mammogram yields a significant number of patients …
mammography, manual classification of mammogram yields a significant number of patients …
[HTML][HTML] The Arabidopsis NPF3 protein is a GA transporter
I Tal, Y Zhang, ME Jørgensen, O Pisanty… - Nature …, 2016 - nature.com
Gibberellins (GAs) are plant hormones that promote a wide range of developmental processes.
While GA signalling is well understood, little is known about how GA is transported or …
While GA signalling is well understood, little is known about how GA is transported or …
Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health
Dogs are the most phenotypically diverse mammalian species, and they possess more
known heritable disorders than any other non-human mammal. Efforts to catalog and …
known heritable disorders than any other non-human mammal. Efforts to catalog and …
[HTML][HTML] An integrated map of structural variation in 2,504 human genomes
Structural variants are implicated in numerous diseases and make up the majority of varying
nucleotides among human genomes. Here we describe an integrated set of eight structural …
nucleotides among human genomes. Here we describe an integrated set of eight structural …