A genetically encoded fluorescent sensor for in vivo imaging of GABA
Current techniques for monitoring GABA (γ-aminobutyric acid), the primary inhibitory
neurotransmitter in vertebrates, cannot follow transients in intact neural circuits. To develop a GABA …
neurotransmitter in vertebrates, cannot follow transients in intact neural circuits. To develop a GABA …
Determination of an effective housekeeping gene for the quantification of mRNA for forensic applications
LI Moreno, CM Tate, EL Knott… - Journal of Forensic …, 2012 - Wiley Online Library
The potential application of mRNA for the identification of biological fluids using molecular
techniques has been a recent development in forensic serology. Constitutively expressed …
techniques has been a recent development in forensic serology. Constitutively expressed …
[HTML][HTML] A targeted bioinformatics assessment of adrenocortical carcinoma reveals prognostic implications of GABA system gene expression
EL Knott, NJ Leidenheimer - International journal of molecular sciences, 2020 - mdpi.com
Adrenocortical carcinoma (ACC) is a rare but deadly cancer for which few treatments exist.
Here, we have undertaken a targeted bioinformatics study of The Cancer Genome Atlas (…
Here, we have undertaken a targeted bioinformatics study of The Cancer Genome Atlas (…
The role of the GABA shunt in prostate cancer metabolic reprogramming and aggressive phenotype
EL Knott, S Miriyala, H Nam, M Panchatcharam… - Cancer Research, 2018 - AACR
The GABA (γ-aminobutyric acid) shunt, a bypass mechanism for a portion of the tricarboxylic
acid (TCA) cycle, is responsible in the mammalian central nervous system for the synthesis …
acid (TCA) cycle, is responsible in the mammalian central nervous system for the synthesis …
Targeted bioinformatics analysis identifies high ABAT transcript expression as a multi-cancer marker of favorable patient prognosis
EL Knott, NJ Leidenheimer - Cancer Research, 2021 - AACR
Unsupervised analysis of γ-aminobutyric acid (GABA) system genes has identified some
genes as correlated with indicators of severity in several cancers. Central to GABA system …
genes as correlated with indicators of severity in several cancers. Central to GABA system …
Prostate cancer cells utilize the GABA shunt to enhance oxidative metabolism
EL Knott, S Miriyala, M Panchatcharam… - Cancer Research, 2019 - AACR
Although an upregulation of aerobic glycolysis (the Warburg effect) is a canonical hallmark
of cancer, it is now recognized that most cancerous cells continue to rely on the TCA cycle as …
of cancer, it is now recognized that most cancerous cells continue to rely on the TCA cycle as …
[HTML][HTML] The HEALing (Helping to End Addiction Long-term SM) Communities Study: Protocol for a cluster randomized trial at the community level to reduce opioid …
Background Opioid overdose deaths remain high in the US Despite having effective interventions
to prevent overdose deaths, there are numerous barriers that impede their adoption. …
to prevent overdose deaths, there are numerous barriers that impede their adoption. …
GABA system expression level changes persist across cancers of many organ systems
EL Knott, NJ Leidenheimer - Cancer Research, 2020 - AACR
… Erika Lynn Knott; Erika Lynn Knott … Citation Format: Erika Lynn Knott, Nancy J. Leidenheimer.
GABA system expression level changes persist across cancers of many organ systems […
GABA system expression level changes persist across cancers of many organ systems […
Assortative mating and mate‐choice contributes to the maintenance of a developmental dimorphism in Streblospio benedicti
EL Ruskie, C Zakas - Journal of Experimental Zoology Part B …, 2023 - Wiley Online Library
… Erika L. Ruskie was responsible for data collection and analysis as well as writing the
original draft. She received an Office of Undergraduate Research Award from NCSU (Summer …
original draft. She received an Office of Undergraduate Research Award from NCSU (Summer …
Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection
…, JD Curtis, A Castoldi, J Cupovic, L Dreesen… - Science …, 2022 - science.org
Type 2 immunity is associated with adipose tissue (AT) homeostasis and infection with
parasitic helminths, but whether AT participates in immunity to these parasites is unknown. We …
parasitic helminths, but whether AT participates in immunity to these parasites is unknown. We …