Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders

…, L Beccari, I Aneas, E Vielmas… - Proceedings of the …, 2015 - National Acad Sciences
Increasing evidence in the last years indicates that the vast amount of regulatory information
contained in mammalian genomes is organized in precise 3D chromatin structures. …

[HTML][HTML] Dual roles of the sterol recognition region in Hedgehog protein modification

R Purohit, DS Peng, E Vielmas, AE Ondrus - Communications biology, 2020 - nature.com
Nature provides a number of mechanisms to encode dynamic information in biomolecules.
In metazoans, there exist rare chemical modifications that occur in entirely unique regimes. …

[PDF][PDF] Sequential response to multiple developmental network circuits encoded in an intronic cis-regulatory module of sea urchin hox11/13b

M Cui, E Vielmas, EH Davidson, IS Peter - Cell reports, 2017 - cell.com
Gene expression in different spatial domains is often controlled by separate cis-regulatory
modules (CRMs), but regulatory states determining CRM activity are not only distinct in space, …

[HTML][HTML] Hedgehog proteins create a dynamic cholesterol interface

A Mafi, R Purohit, E Vielmas, AR Lauinger, B Lam… - PLoS …, 2021 - journals.plos.org
During formation of the Hedgehog (Hh) signaling proteins, cooperative activities of the
Hedgehog INTein (Hint) fold and Sterol Recognition Region (SRR) couple autoproteolysis to …

Defining roles of the sterol recognition region in Hedgehog cholesterolyation

R Purohit, E Vielmas, DS Peng, A Ondrus - The FASEB Journal, 2020 - Wiley Online Library
The Hedgehog (Hh) signaling pathway plays an essential role during embryogenesis and
when dysregulated, can lead to human cancer (basal cell carcinomas) and the most lethal …

Publisher Correction: Dual roles of the sterol recognition region in Hedgehog protein modification

R Purohit, DS Peng, E Vielmas… - Communications …, 2020 - ncbi.nlm.nih.gov
… Peng, Erika Vielmas, and Alison E. Ondrus corresponding author …

The Early Triassic recovery period: Exploring ecology and evolution in marine benthic communities following the Permian-Triassic mass extinction

E Petsios - 2016 - search.proquest.com
The Permian-Triassic mass extinction was the largest extinction of the Phanerozoic, and led
to significant taxonomic loss and ecological restructuring in both marine and terrestrial …

Building a Gene Regulatory Network in Adult Mouse Skeletal Muscle Following Nerve Injury: Transcriptome Characterization and New Model for Functional cis …

G Hernandez - 2013 - thesis.library.caltech.edu
The essential functional linkages of gene regulatory networks (GRNs) consist of the
interactions between cis-regulatory DNA sequences and trans-acting regulatory factors. These …

[PDF][PDF] Functional cis-Regulatory Analysis In Vivo

G Hernandez - 2012 - core.ac.uk
The essential functional linkages of gene regulatory networks (GRNs) consist of the
interactions between cis-regulatory DNA sequences and trans-acting regulatory factors. These …

[CITATION][C] Biol. 503 May 18, 2010

E Vielmas