Multicellular organisms balance oxygen delivery and toxicity by having oxygen pass through
several barriers before cellular delivery. In human cell culture, these physiologic barriers …

Hypoxia is a deficiency in oxygen delivery to tissues and is connected to physiological and
pathophysiological processes such as embryonic development and cancer. The master …

Cells remodel splicing and translation machineries to mount specialized gene expression
responses to stress. Here, we show that hypoxic human cells in 2D and 3D culture models …

Overlapping or convergent stress-activated molecular pathways exist to coordinate cell fate
in response to stimuli such as hypoxia, oxidative stress, DNA damage, and unfolded proteins…

Translational control is a focal point of gene regulation, especially during periods of cellular
stress. Cap-dependent translation via the eIF4F complex is by far the most common pathway …

Hypoxia occurs when there is a deficiency in oxygen delivery to tissues and is connected to
physiological and pathophysiological processes such as embryonic development, wound …

Dialectical behaviour therapy (DBT) and acceptance and commitment therapy (ACT) are
third-wave cognitive behavioural therapies that are beginning to show promise in the treatment …

Wild fish living downstream of wastewater treatment plants (WWTPs) often have increased
body condition factors or body mass indices compared to upstream fish. This observation has …

Estrogens affect the development, maturation, and function of multiple organ systems,
including the immune system. One of the main targets of estrogens in the immune system is the …

For caregivers of minimally communicative individuals, providing support in the absence of
clearly meaningful responses is ethically fraught. We conducted a secondary analysis of …