Insulin receptor (IR) signaling is central to normal metabolic control and is dysregulated in
metabolic diseases such as type 2 diabetes. We report here that IR is incorporated into …

Viral–host interactomes map the complex architecture of an evolved arms race during host
cell invasion. mRNA and protein interactomes reveal elaborate targeting schemes, yet …

Engineering stochastic fluctuations of gene expression (or “noise”) is integral to precisely
bias cellular-fate decisions and statistical phenotypes in both single-cell and multi-cellular …

Latently infected T cells able to reinitiate viral propagation throughout the body remain a
major barrier to curing HIV. Distinguishing between latently infected cells and uninfected cells …

Label-free imaging through two-photon autofluorescence (2PAF) of NAD(P)H allows for non-destructive
and high-resolution visualization of cellular activities in living systems. However, …

Human immunodeficiency virus (HIV) can infect cells and take a quiescent and nonexpressive
state called latency. In this study, we report insights provided by label-free, gradient light …

Quantitative phase imaging (QPI) has emerged as a non-destructive tool for label-free imaging
which helps understand the underlying physiological phenomena [1-7]. In this paper, we …

A disparate array of plasma/serum markers provides evidence for chronic inflammation in
human prediabetes, a condition that is most closely replicated by standard mouse models of …

Objective To evaluate whether endometrial molecular profiles distinguish subsets of
patients according to clinical characteristics, and to infer dysregulated immune networks, by …

Adipocytes are key regulators of human metabolism, and their dysfunction in insulin signaling
is central to metabolic diseases including type II diabetes mellitus (T2D). However, the …