[PDF][PDF] Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

…, K Zandi, S Tao, TR Horton, EN Beagle, EA Mahar… - Cell, 2021 - cell.com
SARS-CoV-2-induced hypercytokinemia and inflammation are critically associated with
COVID-19 severity. Baricitinib, a clinically approved JAK1/JAK2 inhibitor, is currently being …

Progenitor cells and clinical outcomes in patients with acute coronary syndromes

…, YA Ko, C Liu, I Hesaroieh, EA Mahar… - Circulation …, 2018 - Am Heart Assoc
Rationale: Circulating progenitor cells (CPCs) mobilize in response to ischemic injury, but
their predictive value remains unknown in acute coronary syndrome (ACS). Objective: We …

[HTML][HTML] Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

…, KA Karunakaran, SA Nelson, EA Mahar… - PLoS …, 2021 - journals.plos.org
HIV associated immune activation (IA) is associated with increased morbidity in people living
with HIV (PLWH) on antiretroviral therapy, and remains a barrier for strategies aimed at …

[HTML][HTML] Flow cytometric data analysis of circulating progenitor cell stability

EA Mahar, L Mou, SS Hayek, AA Quyyumi, EK Waller - Data in Brief, 2017 - Elsevier
A recent publication by Mekonnen et al. demonstrated that among women with non-obstructive
coronary artery disease, higher levels of circulating progenitor cells in the blood (CPC), …

[HTML][HTML] Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

…, K Zandi, S Tao, TR Horton, EN Beagle, EA Mahar… - bioRxiv - ncbi.nlm.nih.gov
Effective therapeutics aimed at mitigating COVID-19 symptoms are urgently needed. SARS-CoV-2
induced hypercytokinemia and systemic inflammation are associated with disease …

Progenitor cells and clinical outcomes in patients with heart failure

…, YA Ko, H Aida, I Hesaroieh, E Mahar… - Circulation: Heart …, 2017 - Am Heart Assoc
Background Endogenous regenerative capacity, assessed as circulating progenitor cell (PC)
numbers, is an independent predictor of adverse outcomes in patients with cardiovascular …

Sex differences in circulating progenitor cells

…, A Samman Tahhan, I Hesaroieh, E Mahar… - Journal of the …, 2017 - Am Heart Assoc
Background Lower levels of circulating progenitor cells (PCs) reflect impaired endogenous
regenerative capacity and are associated with aging, vascular disease, and poor outcomes. …

Cost-effectiveness of use of 20-valent pneumococcal conjugate vaccine among adults in Germany

…, D Urbanski-Rini, J Schiller, E Mahar… - Expert Review of …, 2023 - Taylor & Francis
Objectives Despite national recommendations for use of pneumococcal vaccines, rates of
community-acquired pneumonia (CAP) and invasive pneumococcal disease (IPD) remain …

[HTML][HTML] Mathematical modeling of pneumococcal transmission dynamics in response to PCV13 infant vaccination in Germany predicts increasing IPD burden due to …

M Horn, C Theilacker, R Sprenger, C von Eiff, E Mahar… - Plos one, 2023 - journals.plos.org
Introduction Two next-generation pneumococcal conjugate vaccines (PCVs), a 15- and a 20-valent
PCV (PCV15 and PCV20), have recently been licensed for use in adults, and PCV15 …

[HTML][HTML] Hierarchical Differences in Defensin Gene Expression in Plasmacytoid Dendritic Cells and Progenitor Cells from Five Different Hematopoietic Stem Cell …

CR Giver, EA Mahar, S Hosoba, J Kowalski, S Seby… - Blood, 2017 - Elsevier
Introduction: We have previously reported that the source of the graft for allogeneic hematopoietic
stem cell transplantation (bone marrow (BM) vs. G-CSF mobilized peripheral blood (G-…