We describe a synthetic approach toward the rapid modification of phenyl-indolyl maleimides
and the discovery of potent Jak3 inhibitor 1 with high selectivity within the Jak kinase family…

Background Siponimod (BAF312), a selective S1P 1 /S1P 5 agonist, reduces disability
progression in secondary progressive MS. Recent observations suggest it could act via S1P 1 /…

We present the result of a search for weakly interacting neutral bosons (X) produced in π− p
interactions at rest and decaying into e+ e− pairs. The data sample searched contains 98 …

We present the result of a measurement of the π 0 electromagnetic transition form factor in the
time-like region of momentum transfer. From a data sample of 54 000 π 0→ e+ e− γ decays…

The reaction π− p→ π 0 n at rest was used as a source of tagged monoenergetic π 0's in a
search for the decay π 0→ e+ e− with the SINDRUM I spectrometer. The measurement …

Dysregulated mRNA splicing is involved in the pathogenesis of many diseases including
cancer, neurodegenerative diseases, and muscular dystrophies such as myotonic dystrophy …

We present the result of a search for weakly interacting neutral bosons ({ital X}) produced in
{pi}{sup {minus}}{ital p} interactions at rest and decaying into {ital e}{sup +}{ital e{minus}} …

This work presents the production method of a vacuum vessel of large diameter and volume
with small density and low Z materials by the use of multiple lamination techniques.

The gut microbiota has been implicated in obesity and cardiometabolic diseases, although
evidence in humans is scarce. We investigated how gut microbiota manipulation by …

Objective This study aimed to examine the intestinal microbiota composition of school‐aged
children in association with (over)weight. Methods The fecal microbiota composition of 295 …