[HTML][HTML] LPS exposure increases maternal corticosterone levels, causes placental injury and increases IL-1β levels in adult rat offspring: relevance to autism

TB Kirsten, LL Lippi, E Bevilacqua, MM Bernardi - PloS one, 2013 - journals.plos.org
Maternal immune activation can induce neuropsychiatric disorders, such as autism and
schizophrenia. Previous investigations by our group have shown that prenatal treatment of rats …

Obesity induced by high-fat diet promotes insulin resistance in the ovary

…, LC Caperuto, E Bevilacqua… - Journal of …, 2010 - joe.bioscientifica.com
Besides the effects on peripheral energy homeostasis, insulin also has an important role in
ovarian function. Obesity has a negative effect on fertility, and may play a role in the …

Changes in apoptosis and Bcl-2 expression in human hyperglycemic, term placental trophoblast

…, IMP Calderon, CR Gonçalves, E Bevilacqua… - Diabetes research and …, 2006 - Elsevier
Apoptosis and its associated regulatory mechanisms are physiological events crucial to the
maintenance of placental homeostasis; imbalance of these processes, however, such as …

Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes

…, RM Souza, FTM Costa, A Pontillo, E Bevilacqua… - Science …, 2020 - science.org
Placental malaria (PM) is associated with severe inflammation leading to abortion, preterm
delivery, and intrauterine growth restriction. Innate immunity responses play critical roles, but …

Participation of the mouse implanting trophoblast in nitric oxide production during pregnancy

S Gagioti, C Scavone, E Bevilacqua - Biology of reproduction, 2000 - academic.oup.com
While considerable progress has been made in elucidating nitric oxide (NO) regulatory
mechanisms in the later stages of gestation, much less is known about its synthesis and role …

The role of polymorphonuclear leukocytes in the resistance to cutaneous Leishmaniasis

GMAC Lima, AL Vallochi, UR Silva, EMAF Bevilacqua… - Immunology letters, 1998 - Elsevier
The massive infiltration by polymorphonuclear leukocytes (PMN) soon after skin infection
with Leishmania major suggests that PMN could participate in reducing parasite load and …

[HTML][HTML] Hyperglycemia induces inflammatory mediators in the human chorionic villous

…, DC Damasceno, MVC Rudge, E Bevilacqua… - Cytokine, 2018 - Elsevier
This study was based on the hypothesis that IL-1β and its central regulator, the inflammasome,
may play a role in the inflammatory condition exhibited by placental tissues from mothers …

Macrophage migration inhibitory factor is up-regulated in human first-trimester placenta stimulated by soluble antigen of Toxoplasma gondii, resulting in increased …

…, DAO Silva, G Sorda, E Bevilacqua… - The American journal of …, 2008 - Elsevier
Considering the potential role of macrophage migration inhibitory factor (MIF) in the inflammation
process in placenta when infected by pathogens, we investigated the production of this …

Effect of Maytenus ilicifolia Mart. on pregnant mice

T Montanari, E Bevilacqua - Contraception, 2002 - Elsevier
Maytenus ilicifolia Mart. is used in Brazilian herbal medicine particularly for stomach
disorders, but it is also used, as in other parts of South America, for fertility control. To verify its …

Changes in the TNF-alpha/IL-10 ratio in hyperglycemia-associated pregnancies

…, AU Borbely, MVC Rudge, E Bevilacqua… - Diabetes Research and …, 2015 - Elsevier
Aims TNF-α is a diabetogenic cytokine associated with adverse outcomes during pregnancy
that can be counterbalanced by IL-10. We have investigated IL-10 and TNF-α balance at …