[HTML][HTML] High dimensional imaging mass cytometry panel to visualize the tumor immune microenvironment contexture

R Elaldi, P Hemon, L Petti, E Cosson… - Frontiers in …, 2021 - frontiersin.org
The integrative analysis of tumor immune microenvironment (TiME) components, their
interactions and their microanatomical distribution is mandatory to better understand tumor …

Expression of LLT1 and its receptor CD161 in lung cancer is associated with better clinical outcome

…, S Knockaert, A Mansuet-Lupo, E Cosson… - …, 2018 - Taylor & Francis
Co-stimulatory and inhibitory receptors expressed by immune cells in the tumor
microenvironment modulate the immune response and cancer progression. Their expression and …

[HTML][HTML] Tumor-associated neutrophils dampen adaptive immunity and promote cutaneous squamous cell carcinoma development

…, P Bourdely, E Salavagione, E Cosson… - Cancers, 2020 - mdpi.com
Cutaneous squamous cell carcinoma (cSCC) development has been linked to immune
dysfunctions but the mechanisms are still unclear. Here, we report a progressive infiltration of …

[HTML][HTML] NK cell and fibroblast-mediated regulation of skin squamous cell carcinoma invasion by CLEC2A is compromised in xeroderma pigmentosum

…, Y Gache, M Basante, E Cosson… - Journal of Investigative …, 2020 - Elsevier
The ability of cancer cells to invade and disseminate can be affected by components of the
surrounding microenvironment. To identify dermal components that regulate the growth of …

A ganglioside-based senescence-associated immune checkpoint

…, F Allain, L Moudombi, P Hofman, E Cosson… - bioRxiv, 2021 - biorxiv.org
Senescent cells accumulate in aging tissues, and their elimination can favor healthy aging 1
- 4 . Therefore, therapeutic interventions targeting cellular senescence may be promising …

A ganglioside-based senescence-associated immune checkpoint ARTICLE EN REVISION FAVORABLE DANS NATURE AGING

…, F Allain, L Moudombi, P Hofman, E Cosson… - 2021 - hal.science
Senescent cells accumulate in aging tissues, and their elimination can favor healthy aging 1-4
. Therefore, therapeutic interventions targeting cellular senescence may be promising …

Evaluation of strains on levator ani muscle: damage induced during delivery for a prediction of patient risks

…, JF Witz, P Lecomte-Grosbras, M Cosson… - … for Medicine: From …, 2017 - Springer
Since childbirth presents a significant risk factor for pathology occurrence of the pelvic floor,
analysis of the phenomena involved during a vaginal delivery is a major issue in obstetrics …

[HTML][HTML] 5-ethyl-2'-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells

…, CF Harrison, H Hilbi, L Scapozza, T Soldati, P Cosson - Plos one, 2022 - journals.plos.org
Klebsiella pneumoniae is the causative agent of a variety of severe infections. Many K.
pneumoniae strains are resistant to multiple antibiotics, and this situation creates a need for new …

Conserved and specific functions of axoneme components in trypanosome motility

…, L Kohl, G Toutirais, J Buisson, J Cosson… - Journal of cell …, 2006 - journals.biologists.com
The Trypanosoma brucei flagellum is unusual as it is attached along the cell body and contains,
in addition to an apparently conventional axoneme, a structure called the paraflagellar …

How we do an anterior sacrospinous ligament fixation for vaginal vault prolapse

…, C Bengler, S Delplanque, M Cosson - International …, 2021 - Springer
Since 2019, all vaginal mesh implants were removed from the market. Since, surgeons
have only the autologous technique left to treat prolapse by vaginal route. The anterior …