The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …

In 2012, the complete genomic sequence of a new and potentially harmful influenza A-like
virus from bats (H17N10) was identified. However, infectious influenza virus was neither …

Influenza is a deadly and costly infectious disease, even during flu seasons when an effective
vaccine has been developed. To improve vaccines against respiratory viruses, a better …

Variant of concern (VOC) Omicron-BA.1 has achieved global predominance in early 2022.
Therefore, surveillance and comprehensive characterization of Omicron-BA.1 in advanced …

Lysine acetylation is a post-translational modification known to regulate protein functions.
Here we identify several acetylation sites of the influenza A virus nucleoprotein (NP), including …

Packaging of the eight genomic RNA segments of influenza A viruses (IAV) into viral particles
is coordinated by segment-specific packaging sequences. How the packaging signals …

Two novel influenza A-like viral genome sequences have recently been identified in Central
and South American fruit bats and provisionally designated “HL17NL10” and “HL18NL11.” …

Influenza is a zoonotic respiratory disease of major public health interest due to its pandemic
potential, and a threat to animals and the human population. The influenza A virus genome …

The deacetylase HDAC6 has tandem catalytic domains and a zinc finger domain (ZnF)
binding ubiquitin (Ub). While the catalytic domain has an antiviral effect, the ZnF facilitates …

A dengue é a mais importante doença causada por arbovírus em humanos e quatro sorotipos
(DENV-1 a 4) são conhecidos. A dengue emergiu como um grande problema de saúde …