User profiles for Eugene A. Kapp

Eugene Kapp

Walter and Eliza Hall Institute of Medical Research
Verified email at wehi.edu.au
Cited by 5670

Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core …

…, BB Haab, RJ Simpson, JS Eddes, EA Kapp… - …, 2005 - Wiley Online Library
HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated
advantages and limitations of many depletion, fractionation, and MS technology platforms; (…

An evaluation, comparison, and accurate benchmarking of several publicly available MS/MS search algorithms: sensitivity and specificity analysis

EA Kapp, F Schütz, LM Connolly, JA Chakel… - …, 2005 - Wiley Online Library
MS/MS and associated database search algorithms are essential proteomic tools for identifying
peptides. Due to their widespread use, it is now time to perform a systematic analysis of …

An aspartyl protease directs malaria effector proteins to the host cell

…, S Günther, PR Gilson, H Patsiouras, EA Kapp… - Nature, 2010 - nature.com
Plasmodium falciparum causes the virulent form of malaria and disease manifestations are
linked to growth inside infected erythrocytes. To survive and evade host responses the …

Mining a tandem mass spectrometry database to determine the trends and global factors influencing peptide fragmentation

EA Kapp, F Schütz, GE Reid, JS Eddes… - Analytical …, 2003 - ACS Publications
A database of 5500 unique peptide tandem mass spectra acquired in an ion trap mass
spectrometer was assembled for peptides derived from proteins digested with trypsin. Peptides …

[HTML][HTML] Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition

…, DW Greening, SK Gopal, H Ji, EA Kapp… - Molecular & cellular …, 2013 - ASBMB
Epithelial-mesenchymal transition (EMT) is a highly conserved morphogenic process defined
by the loss of epithelial characteristics and the acquisition of a mesenchymal phenotype. …

BAK core dimers bind lipids and can be bridged by them

AD Cowan, NA Smith, JJ Sandow, EA Kapp… - Nature structural & …, 2020 - nature.com
BAK and BAX are essential mediators of apoptosis that oligomerize in response to death
cues, thereby causing permeabilization of the mitochondrial outer membrane. Their transition …

Characterization and identification of dityrosine cross-linked peptides using tandem mass spectrometry

S Mukherjee, EA Kapp, A Lothian, AM Roberts… - Analytical …, 2017 - ACS Publications
The use of mass spectrometry coupled with chemical cross-linking of proteins has become
a powerful tool for proteins structure and interactions studies. Unlike structural analysis of …

[PDF][PDF] Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

…, N Burgdorf, M Maurin, EA Kapp… - Cell Reports, 2022 - cell.com
Despite its crucial role in initiation of cytotoxic immune responses, the molecular pathways
underlying antigen cross-presentation remain incompletely understood. The mechanism of …

Difference gel electrophoresis analysis of Ras‐transformed fibroblast cell‐derived exosomes

H Ji, N Erfani, BJ Tauro, EA Kapp, HJ Zhu… - …, 2008 - Wiley Online Library
Exosomes are membrane vesicles of endocytic origin released by many cell types. The
molecular composition of exosomes reflects the specialised functions of their original cells. For …

The inner ear proteome of fish

ORB Thomas, SE Swearer, EA Kapp, P Peng… - The FEBS …, 2019 - Wiley Online Library
The mechanisms that underpin the formation, growth and composition of otoliths, the
biomineralized stones in the inner ear of fish, are largely unknown, as only a few fish inner ear …