The focus of my group is on the study of the intestinal microbes and how they interact with
the host. This relationship is fundamental to our health and, when perturbed, the …

Background: Growing evidence shows that dietary factors can dramatically alter the gut
microbiome in ways that contribute to metabolic disturbance and progression of obesity. In this …

T cell infiltration of solid tumors is associated with favorable patient outcomes, yet the mechanisms
underlying variable immune responses between individuals are not well understood. …

After ingestion of ginseng, the bioavailability of its parent compounds is low and enteric
microbiota plays an important role in parent compound biotransformation to their metabolites. …

Colonic microbiota ferment non-absorbed dietary fiber to produce prodigious amounts of short
chain fatty acids (SCFAs) that benefit the host through a myriad of metabolic, trophic, and …

Literature regarding the development of adolescent and young adult (AYA) cancer programs
has been dominantly informed by pediatric centers and practitioners. However, the majority …

Models of electrical activity in cardiac cells have become important research tools as they can
provide a quantitative description of detailed and integrative physiology. However, cardiac …

Mucosal injury and inflammation are cardinal manifestations of inflammatory bowel diseases
(IBD), arising when the effects of cytotoxic factors and conditions overwhelm the cell's …

Background Chronic sinusitis is universal in cystic fibrosis (CF) and our current treatments
are ineffective in reversing sinus disease. The objective of this work was to determine if …

The composite human microbiome of Western populations has probably changed over the
past century, brought on by new environmental triggers that often have a negative impact on …