Thresholds for thermal damage to normal tissues: an update
PS Yarmolenko, EJ Moon, C Landon… - International Journal …, 2011 - Taylor & Francis
The purpose of this review is to summarise a literature survey on thermal thresholds for
tissue damage. This review covers published literature for the consecutive years from 2002–2009…
tissue damage. This review covers published literature for the consecutive years from 2002–2009…
[HTML][HTML] Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
Switching to a glycolytic metabolism is a rapid adaptation of tumor cells to hypoxia.
Although this metabolic conversion may primarily represent a rescue pathway to meet the …
Although this metabolic conversion may primarily represent a rescue pathway to meet the …
Effect of aerobic exercise on tumor physiology in an animal model of human breast cancer
…, MQ Potter, E Jung Moon… - Journal of applied …, 2010 - journals.physiology.org
Recent epidemiologic studies report that regular exercise may be associated with substantial
reductions in cancer-specific and all-cause mortality following a breast cancer diagnosis. …
reductions in cancer-specific and all-cause mortality following a breast cancer diagnosis. …
Dual roles of NRF2 in tumor prevention and progression: possible implications in cancer treatment
EJ Moon, A Giaccia - Free Radical Biology and Medicine, 2015 - Elsevier
The cap’n’collar (CNC) family serves as cellular sensors of oxidative and electrophilic stresses
and shares structural similarities including basic leucine zipper (bZIP) and CNC domains. …
and shares structural similarities including basic leucine zipper (bZIP) and CNC domains. …
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
Hyperthermia (HT) is a strong adjuvant treatment with radiotherapy and chemotherapy because
it causes tumor reoxygenation. However, the detailed molecular mechanisms of how HT …
it causes tumor reoxygenation. However, the detailed molecular mechanisms of how HT …
[HTML][HTML] The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
Hypoxia plays a critical role in tumor progression including invasion and metastasis. To
determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen …
determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen …
The potential role of intrinsic hypoxia markers as prognostic variables in cancer
Tumor hypoxia is related to tumor progression and therapy resistance, which leads to poor
patient outcome. It has been suggested that measuring the hypoxic status of a tumor helps to …
patient outcome. It has been suggested that measuring the hypoxic status of a tumor helps to …
Neutralization of PD-L2 is essential for overcoming immune checkpoint blockade resistance in ovarian cancer
…, TTC Yang, AN Diep, GM Cherf, Y Xu, EJ Moon… - Clinical cancer …, 2021 - AACR
Purpose: Ovarian cancer represents a major clinical hurdle for immune checkpoint blockade
(ICB), with reported low patient response rates. We found that the immune checkpoint …
(ICB), with reported low patient response rates. We found that the immune checkpoint …
The importance of hypoxia in radiotherapy for the immune response, metastatic potential and FLASH-RT
EJ Moon, K Petersson, MM Olcina - International journal of …, 2022 - Taylor & Francis
Purpose Hypoxia (low oxygen) is a common feature of solid tumors that has been intensely
studied for more than six decades. Here we review the importance of hypoxia to radiotherapy …
studied for more than six decades. Here we review the importance of hypoxia to radiotherapy …
[HTML][HTML] Evaluation of salmon, tuna, and beef freshness using a portable spectrometer
There has been strong demand for the development of an accurate but simple method to
assess the freshness of food. In this study, we demonstrated a system to determine food …
assess the freshness of food. In this study, we demonstrated a system to determine food …