Age‐related changes in hippocampal‐dependent synaptic plasticity and memory mediated by p75 neurotrophin receptor
The plasticity mechanisms in the nervous system that are important for learning and memory
are greatly impacted during aging. Notably, hippocampal‐dependent long‐term plasticity …
are greatly impacted during aging. Notably, hippocampal‐dependent long‐term plasticity …
[HTML][HTML] CD137 negatively affects “browning” of white adipose tissue during cold exposure
…, A Moliner, ES Lee, E Nickles, E Sim… - Journal of Biological …, 2020 - ASBMB
Prolonged cold exposure stimulates the formation of brownlike adipocytes expressing UCP1
(uncoupling-protein-1) in subcutaneous white adipose tissue which, together with classical …
(uncoupling-protein-1) in subcutaneous white adipose tissue which, together with classical …
[HTML][HTML] AraC interacts with p75NTR transmembrane domain to induce cell death of mature neurons
V Lopes-Rodrigues, P Boxy, E Sim, DI Park… - Cell Death & …, 2023 - nature.com
Cytosine arabinoside (AraC) is one of the main therapeutic treatments for several types of
cancer, including acute myeloid leukaemia. However, after a high-dose AraC chemotherapy …
cancer, including acute myeloid leukaemia. However, after a high-dose AraC chemotherapy …
[HTML][HTML] Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains
N Zhang, L Kisiswa, A Ramanujan, Z Li, EW Sim… - Journal of Biological …, 2021 - ASBMB
The p75 neurotrophin receptor (p75 NTR ) is a critical mediator of neuronal death and tissue
remodeling and has been implicated in various neurodegenerative diseases and cancers. …
remodeling and has been implicated in various neurodegenerative diseases and cancers. …
Sustained anti-obesity effects of life-style change and anti-inflammatory interventions after conditional inactivation of the activin receptor ALK7
RK Srivastava, ES Lee, E Sim, NC Sheng, CF Ibáñez - bioRxiv, 2020 - biorxiv.org
Life-style change and anti-inflammatory interventions have only transient effects in obesity.
It is not clear how benefits obtained by these treatments can be maintained longer term, …
It is not clear how benefits obtained by these treatments can be maintained longer term, …
Synthesis, X-ray structural and spectroscopic study of new silyl-substituted triosmium clusters
HG Ang, B Chang, WL Kwik, ESH Sim - Journal of organometallic chemistry, 1994 - Elsevier
The 2-pyridyldimethylsilane, 2-(CH 3 ) 2 SiHC 5 H 4 NLH reacts with Os 3 (μ-H) 2 (CO) 10 ]
to afford the novel cluster [Os 3 (μ-H) 2 (CO) 10 L 2 ] 1 in which each of the ligands L has …
to afford the novel cluster [Os 3 (μ-H) 2 (CO) 10 L 2 ] 1 in which each of the ligands L has …
Studying Abroad in Shanghai: Exploring How a Living-Learning Community Impacts Students' Sociocultural Understandings of China
S Erbes, R Jackson, E Sim - Journal of Higher Education Theory …, 2022 - articlearchives.co
This is a qualitative case study that explored how a study abroad program based in Shanghai
impacted five undergraduates’ sociocultural understandings of China. The purpose of this …
impacted five undergraduates’ sociocultural understandings of China. The purpose of this …
AraC binds the p75NTR transmembrane domain to induce neurodegeneration in mature neurons
V Lopes-Rodrigues, P Boxy, E Sim, DI Park… - bioRxiv, 2021 - biorxiv.org
Background Cytosine arabinoside (AraC) is one of the main therapeutic treatments for
several types of cancer including acute myeloid leukaemia. However, after high dose AraC …
several types of cancer including acute myeloid leukaemia. However, after high dose AraC …
Structural and functional elucidation of NF-κB signaling by the p75 neurotrophin receptor through recruitment of TRADD
N Zhang, L Kisiswa, A Ramanujan, Z Li, EW Sim… - bioRxiv, 2021 - biorxiv.org
p75 neurotrophin receptor (p75 NTR ) is a critical mediator of neuronal death and tissue
remodeling and has been implicated in various neurodegenerative diseases. The death domain …
remodeling and has been implicated in various neurodegenerative diseases. The death domain …
Correction: Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains
N Zhang, L Kisiswa, A Ramanujan, Z Li, EW Sim… - Journal of Biological …, 2022 - ASBMB
The p75 neurotrophin receptor (p75 NTR) is a critical mediator of neuronal death and tissue
remodeling and has been implicated in various neurodegenerative diseases and cancers. …
remodeling and has been implicated in various neurodegenerative diseases and cancers. …