An elegant mind: learning and memory in Caenorhabditis elegans

EL Ardiel, CH Rankin - Learning & memory, 2010 - learnmem.cshlp.org
This article reviews the literature on learning and memory in the soil-dwelling nematode
Caenorhabditis elegans. Paradigms include nonassociative learning, associative learning, and …

The importance of touch in development

EL Ardiel, CH Rankin - Paediatrics & child health, 2010 - academic.oup.com
Developmental delay is common in children deprived of normal sensory stimulation – for
example, in premature neonates and some institutionalized children. Touch has emerged as an …

[PDF][PDF] An afferent neuropeptide system transmits mechanosensory signals triggering sensitization and arousal in C. elegans

…, Y Tanizawa, Y Cho, B Zhao, JY Alex, EL Ardiel… - Neuron, 2018 - cell.com
Sensitization is a simple form of behavioral plasticity by which an initial stimulus, often
signaling danger, leads to increased responsiveness to subsequent stimuli. Cross-modal …

[PDF][PDF] Visualizing calcium flux in freely moving nematode embryos

EL Ardiel, A Kumar, J Marbach, R Christensen… - Biophysical journal, 2017 - cell.com
The lack of physiological recordings from Caenorhabditis elegans embryos stands in stark
contrast to the comprehensive anatomical and gene expression datasets already available. …

Accumulation of laminin monomers in Drosophila glia leads to glial endoplasmic reticulum stress and disrupted larval locomotion

LM Petley-Ragan, EL Ardiel, CH Rankin… - Journal of …, 2016 - Soc Neuroscience
The nervous system is surrounded by an extracellular matrix composed of large glycoproteins,
including perlecan, collagens, and laminins. Glial cells in many organisms secrete laminin…

[HTML][HTML] Habituation as an adaptive shift in response strategy mediated by neuropeptides

EL Ardiel, AJ Yu, AC Giles, CH Rankin - npj Science of Learning, 2017 - nature.com
Habituation is a non-associative form of learning characterized by a decremented response
to repeated stimulation. It is typically framed as a process of selective attention, allowing …

Dopamine receptor DOP-4 modulates habituation to repetitive photoactivation of a C. elegans polymodal nociceptor

EL Ardiel, AC Giles, JY Alex, TH Lindsay… - Learning & …, 2016 - learnmem.cshlp.org
Habituation is a highly conserved phenomenon that remains poorly understood at the molecular
level. Invertebrate model systems, like Caenorhabditis elegans, can be a powerful tool …

[HTML][HTML] Mechanisms of plasticity in a Caenorhabditis elegans mechanosensory circuit

T Bozorgmehr, EL Ardiel, AH McEwan… - Frontiers in …, 2013 - frontiersin.org
Despite having a small nervous system (302 neurons) and relatively short lifespan (14–21
days), the nematode Caenorhabditis elegans has a substantial ability to change its behavior …

Insights into the roles of CMK-1 and OGT-1 in interstimulus interval-dependent habituation in Caenorhabditis elegans

EL Ardiel, TA McDiarmid… - … of the Royal …, 2018 - royalsocietypublishing.org
Habituation is a ubiquitous form of non-associative learning observed as a decrement in
responding to repeated stimulation that cannot be explained by sensory adaptation or motor …

Intensity discrimination deficits cause habituation changes in middle-aged Caenorhabditis elegans

TA Timbers, AC Giles, EL Ardiel, RA Kerr… - Neurobiology of …, 2013 - Elsevier
The ability to learn and remember is critical for all animals to survive in the ever-changing
environment. As we age, many of our biological faculties decay and of these, decline in …