… Evangelos Evangelou, research associate … John Ioannidis, Nikolaos Patsopoulos, and
Evangelos Evangelou argue that, although meta-analyses often measure heterogeneity …

Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed
the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 …

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

Background Several approaches are available for evaluating heterogeneity in meta-analysis.
Sensitivity analyses are often used, but these are often implemented in various non-…

Background The cause of multiple sclerosis is believed to involve environmental exposure
and genetic susceptibility. We aimed to summarise the environmental risk factors that have …

Background Type 2 diabetes mellitus (T2DM) is a global epidemic associated with increased
health expenditure, and low quality of life. Many non-genetic risk factors have been …

Meta-analysis of genome-wide association studies (GWASs) has become a popular method
for discovering genetic risk variants. Here, we overview both widely applied and newer …

Genome-wide association studies (GWAS) in coronary artery disease (CAD) had identified
66 loci at'genome-wide significance'(P< 5× 10− 8) at the time of this analysis, but a much …

Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral
density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative …

Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …