User profiles for Evangelos Handakas

Evangelos Handakas (Chandakas)

Cambridge University - Department of Chemistry
Verified email at cam.ac.uk
Cited by 556

Determinants of accelerated metabolomic and epigenetic aging in a UK cohort

…, R Climaco Pinto, M Ala-Korpela, E Handakas… - Aging cell, 2020 - Wiley Online Library
Markers of biological aging have potential utility in primary care and public health. We
developed a model of age based on untargeted metabolic profiling across multiple platforms, …

The built environment as determinant of childhood obesity: a systematic literature review

D Malacarne, E Handakas, O Robinson… - Obesity …, 2022 - Wiley Online Library
We evaluated the epidemiological evidence on the built environment and its link to childhood
obesity, focusing on environmental factors such as traffic noise and air pollution, as well as …

A systematic review of metabolomic studies of childhood obesity: State of the evidence for metabolic determinants and consequences

E Handakas, CH Lau, R Alfano, VL Chatzi… - Obesity …, 2022 - Wiley Online Library
Childhood obesity has become a global epidemic and carries significant long‐term consequences
to physical and mental health. Metabolomics, the global profiling of small molecules …

PhenoMeNal: processing and analysis of metabolomics data in the cloud

…, A Gonzalez-Beltran, UL Günther, E Handakas… - …, 2019 - academic.oup.com
Background Metabolomics is the comprehensive study of a multitude of small molecules to
gain insight into an organism's metabolism. The research field is dynamic and expanding …

Perspectives and challenges of epigenetic determinants of childhood obesity: a systematic review

R Alfano, O Robinson, E Handakas, TS Nawrot… - Obesity …, 2022 - Wiley Online Library
The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …

[HTML][HTML] Metabolic profiles of ultra-processed food consumption and their role in obesity risk in British children

E Handakas, K Chang, N Khandpur, EP Vamos… - Clinical Nutrition, 2022 - Elsevier
Background & aims Higher consumption of ultra-processed foods (UPF) has been associated
with childhood obesity, but underlying mechanisms remain unclear. We investigated …

Integrated exposure and risk characterization of bisphenol-A in Europe

DA Sarigiannis, SP Karakitsios, E Handakas… - Food and Chemical …, 2016 - Elsevier
The current study aims at a comprehensive risk characterization of bisphenol A (BPA) supported
by an integrated exposure modelling framework that comprises far field and near field …

Neurodevelopmental exposome: The effect of in utero co-exposure to heavy metals and phthalates on child neurodevelopment

DA Sarigiannis, N Papaioannou, E Handakas… - Environmental …, 2021 - Elsevier
In this study, the exposome paradigm has been applied on a mother-child cohort adopting
an optimised untargeted metabolomics approach for human urine followed by advanced …

[HTML][HTML] The exposome approach to study children's health

E Handakas, O Robinson, JE Laine - Current Opinion in Environmental …, 2023 - Elsevier
The exposome represents an interdisciplinary science and promising field of research that
can identify how multiple facets of the environment influences health across the lifespan. A …

[HTML][HTML] Cord blood metabolic signatures predictive of childhood overweight and rapid growth

E Handakas, P Keski-Rahkonen, L Chatzi… - International Journal of …, 2021 - nature.com
Introduction Metabolomics may identify biological pathways predisposing children to the
risk of overweight and obesity. In this study, we have investigated the cord blood metabolic …