Novel cell lines derived from adult human ventricular cardiomyocytes

…, L Palenzuela, WF Walker, E Hernandez… - Journal of molecular and …, 2005 - Elsevier
Background. – We have established proliferating human cardiomyocyte cell lines derived
from non-proliferating primary cultures of adult ventricular heart tissue, using a novel method …

Prevalence and correlates of non-suicidal self-injury among lesbian, gay, bisexual, and transgender individuals: A systematic review and meta-analysis

…, CM Sanzari, SM Cheek, EM Hernandez - Clinical psychology …, 2019 - Elsevier
The current review presents a meta-analysis of the existing empirical literature on the prevalence
of non-suicidal self-injury (NSSI) among lesbian, gay, bisexual, and transgender (LGBT…

A behavioral and cognitive neuroscience perspective on impulsivity, suicide, and non-suicidal self-injury: Meta-analysis and recommendations for future research

RT Liu, ZM Trout, EM Hernandez, SM Cheek… - Neuroscience & …, 2017 - Elsevier
We conducted a meta-analysis of neurobehavioral and neurocognitive indices of impulsivity
in relation to suicidal thoughts and behaviors, as well as non-suicidal self-injury (NSSI). In …

Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation

RW Gilkerson, EA Schon, E Hernandez… - The Journal of cell …, 2008 - rupress.org
Mitochondrial DNA (mtDNA) is packaged into DNA-protein assemblies called nucleoids, but
the mode of mtDNA propagation via the nucleoid remains controversial. Two mechanisms …

[HTML][HTML] CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

…, A Fossati, AF Brilot, D Diwanji, E Hernandez… - Research …, 2021 - ncbi.nlm.nih.gov
The SARS-CoV-2 protein Nsp2 has been implicated in a wide range of viral processes, but
its exact functions, and the structural basis of those functions, remain unknown. Here, we …

Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp

…, DR Boyer, MW Martynowycz, E Hernandez… - Nature structural & …, 2018 - nature.com
The atomic structure of the infectious, protease-resistant, β-sheet-rich and fibrillar mammalian
prion remains unknown. Through the cryo-EM method MicroED, we reveal the sub-…

Depression, social support, and long-term risk for coronary heart disease in a 13-year longitudinal epidemiological study

RT Liu, EM Hernandez, ZM Trout, EM Kleiman… - Psychiatry …, 2017 - Elsevier
Depression has been linked with long-term risk for a variety of physical health ailments,
including coronary heart disease (CHD). Little is known about resilience factors that may …

[HTML][HTML] Host response during unresolved urinary tract infection alters female mammary tissue homeostasis through collagen deposition and TIMP1

…, MF Ciccone, IA Diaz, AA Biswas, E Hernandez… - Nature …, 2024 - nature.com
Exposure to pathogens throughout a lifetime influences immunity and organ function. Here,
we explore how the systemic host-response to bacterial urinary tract infection (UTI) induces …

[HTML][HTML] An ELF4 hypomorphic variant results in NK cell deficiency

…, S Mahapatra, EK Moore, ER Hernandez… - JCI insight, 2022 - ncbi.nlm.nih.gov
NK cell deficiencies (NKD) are a type of primary immune deficiency in which the major
immunologic abnormality affects NK cell number, maturity, or function. Since NK cells contribute to …

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

…, J Glasgow, CQ Le, Y Zhang, D Diwanji, E Hernandez… - Structure, 2023 - cell.com
The SARS-CoV-2 Omicron variant, with 15 mutations in Spike receptor-binding domain (Spike-RBD),
renders virtually all clinical monoclonal antibodies against WT SARS-CoV-2 …