In recent years, great advances have been made in the field of collection, storage, and analysis
of biological samples. Large collections of samples, biobanks, have been established in …

Over the recent years, many advances have been made in the research of the genetic factors
of pregnancy complications. In this work, we use publicly available data repositories, such …

Pregnancy loss is the most frequent complication of a pregnancy which is devastating for
affected families and poses a significant challenge for the health care system. Genetic factors …

Complications endangering mother or fetus affect around one in seven pregnant women.
Investigation of the genetic susceptibility to such diseases is of high importance for better …

Thousands of yeast genomes have been sequenced with both traditional and long-read
technologies, and multiple observations about modes of genome evolution for both wild and …

Protein synthesis (translation) is one of the fundamental processes occurring in the cells of
living organisms. Translation can be divided into three key steps: initiation, elongation, and …

Yeast self-perpetuating protein aggregates (yeast prions) provide a framework to investigate
the interaction of misfolded proteins with the protein quality control machinery. The major …

Accurate annotation of putative loss-of-function (pLoF) variants is an important problem in
human genomics and disease, which recently drew substantial attention. Since such variants …

The Peterhof genetic collection (PGC) of yeast Saccharomyces cerevisiae is one of the rare
examples of a large genetic collection established independently of reference S288C strain. …

Objective To test the hypothesis that the prevalence and clinical effect of cerebral autosomal
dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) have …