Functional analysis of Lactobacillus rhamnosus GG pili in relation to adhesion and immunomodulatory interactions with intestinal epithelial cells

…, HLP Tytgat, TLA Verhoeven, E Marien… - Applied and …, 2012 - Am Soc Microbiol
Lactobacillus rhamnosus GG, a probiotic with good survival capacity in the human gut, has
well-documented adhesion properties and health effects. Recently, spaCBA-encoded pili that …

Non‐small cell lung cancer is characterized by dramatic changes in phospholipid profiles

E Marien, M Meister, T Muley, S Fieuws… - … Journal of Cancer, 2015 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) is the leading cause of cancer death globally. To
develop better diagnostics and more effective treatments, research in the past decades has …

[HTML][HTML] Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma

E Marien, M Meister, T Muley, TG Del Pulgar, R Derua… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer death. Beyond first line treatment, few therapeutic
options are available, particularly for squamous cell carcinoma (SCC). Here, we have …

[HTML][HTML] Radiosafe micro-computed tomography for longitudinal evaluation of murine disease models

N Berghen, K Dekoster, E Marien, J Dabin, A Hillen… - Scientific reports, 2019 - nature.com
Implementation of in vivo high-resolution micro-computed tomography (µCT), a powerful tool
for longitudinal analysis of murine lung disease models, is hampered by the lack of data on …

[PDF][PDF] ORP5/8 and MIB/MICOS link ER-mitochondria and intra-mitochondrial contacts for non-vesicular transport of phosphatidylserine

…, AM Kivelä, C Sauvanet, R Le Bars, E Marien… - Cell reports, 2022 - cell.com
Mitochondria are dynamic organelles essential for cell survival whose structural and
functional integrity rely on selective and regulated transport of lipids from/to the endoplasmic …

[HTML][HTML] Longitudinal microcomputed tomography-derived biomarkers for lung metastasis detection in a syngeneic mouse model: added value to bioluminescence …

E Marien, A Hillen, F Vanderhoydonc… - Laboratory …, 2017 - nature.com
With more patients dying from metastasis than from primary cancers, metastasis is a very
important area in cancer research. Investigators thereby heavily rely on animal models of …

ORP5 transfers phosphatidylserine to mitochondria and regulates mitochondrial calcium uptake at endoplasmic reticulum-mitochondria contact sites

…, A Houcine, A Arora, AM Kivelä, MA Xingjie, E Marien… - BioRxiv, 2019 - biorxiv.org
Mitochondria are dynamic organelles essential for cell survival whose structural and
functional integrity rely on selective and regulated transport of lipids from/to the endoplasmic …

Remodeling of phospholipid composition in colon cancer cells by 1α, 25 (OH) 2D3 and its analogs

C Leyssens, E Marien, L Verlinden, R Derua… - The Journal of steroid …, 2015 - Elsevier
Alterations in cellular phospholipid composition are emerging as important traits in the
development and progression of cancer. In this study we investigated the effects of 1α,25-…

ORP5/8 AND MIB/MICOS LINK ER-MITOCHONDRIA AND INTRAMITOCHONDRIAL CONTACTS FOR NON-VESICULAR TRANSPORT OF PHOSPHATIDYLSERINE

…, AM Kivelä, C Sauvanet, RL Bars, E Marien… - 2019 - europepmc.org
Mitochondria are dynamic organelles essential for cell survival whose structural and
functional integrity rely on selective and regulated transport of lipids from/to the endoplasmic …

[PDF][PDF] Non-small cell lung cancer (NSCLC) is characterized by dramatic changes in phospholipid profiles

E Marien, M Meister, T Muley, S Fieuws, S Bordel… - cyberleninka.org
Non-small cell lung cancer (NSCLC) is the leading cause of cancer death globally. In order
to develop better diagnostics and more effective treatments, research in the past decades …