First days in the life of naive human B lymphocytes infected with Epstein-Barr virus
…, P Mrozek-Gorska, M Bouvet, A Sugimoto, E Akidil… - MBio, 2019 - Am Soc Microbiol
Epstein-Barr virus (EBV) infects and activates resting human B lymphocytes, reprograms
them, induces their proliferation, and establishes a latent infection in them. In established EBV-…
them, induces their proliferation, and establishes a latent infection in them. In established EBV-…
[HTML][HTML] Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection
E Akidil, M Albanese, A Buschle, A Ruhle, D Pich… - PLoS …, 2021 - journals.plos.org
Gene editing is now routine in all prokaryotic and metazoan cells but has not received much
attention in immune cells when the CRISPR-Cas9 technology was introduced in the field of …
attention in immune cells when the CRISPR-Cas9 technology was introduced in the field of …
CRISPR-Cas9-mediated gene editing in primary human B cells identifies critical cellular factors for Epstein-Barr virus infection
E Akidil - 2023 - edoc.ub.uni-muenchen.de
In humans, Epstein-Barr virus (EBV) infection can cause Infectious Mononucleosis and is
associated with various malignancies, eg Burkitt’s lymphoma, Hodgkin’s lymphoma, and …
associated with various malignancies, eg Burkitt’s lymphoma, Hodgkin’s lymphoma, and …
Systematic analysis of Epstein-Barr virus genes and their individual contribution to virus production and composition
YFA Chen, B Mocanu, E Akidil, D Pich, J Mautner… - bioRxiv, 2021 - biorxiv.org
Epstein-Barr virus (EBV), a member of the large herpesvirus family is a very complex human
γ-herpesvirus. Its complexity with respect to viral gene regulation, its preferred latent life …
γ-herpesvirus. Its complexity with respect to viral gene regulation, its preferred latent life …
EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus–infected B cells
Epstein-Barr virus (EBV) is a human tumor virus which preferentially infects resting human B
cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent …
cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent …
Inhibition of PLK1-dependent phosphorylation of EBNA2 promotes EBV-induced carcinogenesis in humanized mice
X Zhang - 2021 - edoc.ub.uni-muenchen.de
… I am also thankful to his lab members, Yen-Fu Adam Chen, Ezgi Akidil, Dagmar Pich, and
so on for sharing biological samples and critical techniques. Without this, the research would …
so on for sharing biological samples and critical techniques. Without this, the research would …
[HTML][HTML] 19th international symposium on Epstein–Barr virus and associated diseases, 29–30 July 2021, Asahikawa, Japan
T Kumai, M Takahara, Y Harabuchi - 2022 - mdpi.com
Simple Summary Novel insights into the basic and translational findings on Epstein–Barr
virus-related diseases were presented at the “19th International Symposium on Epstein–Barr …
virus-related diseases were presented at the “19th International Symposium on Epstein–Barr …
Inhibition of PLK1-dependent EBNA2 phosphorylation promotes lymphomagenesis in EBV-infected mice
… We thank Dagmar Pich, Yen-Fu Adam Chen, Ezgi Akidil for all the excellent advice they …
Pich D, Mrozek-Gorska P, Bouvet M, Sugimoto A, Akidil E, Grundhoff A, Hamperl S, Ling PD, …
Pich D, Mrozek-Gorska P, Bouvet M, Sugimoto A, Akidil E, Grundhoff A, Hamperl S, Ling PD, …
PLK1‐dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV‐infected mice
… We thank Dagmar Pich, Yen-Fu Adam Chen, and Ezgi Akidil for all the excellent advice
they gave. We thank Kerstin Heise, Michaela Kroetz-Fahning, and Andreas Klaus for expert …
they gave. We thank Kerstin Heise, Michaela Kroetz-Fahning, and Andreas Klaus for expert …
The EBNA2-EBF1 complex promotes oncogenic MYC expression levels and metabolic processes required for cell cycle progression of Epstein-Barr virus-infected B …
Epstein-Barr virus (EBV) is a human tumor virus, which preferentially infects resting human
B cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent …
B cells. Upon infection in vitro, EBV activates and immortalizes these cells. The viral latent …