Despite extraordinary advances that have been achieved in the last few decades, cancer
continues to represent a leading cause of mortality worldwide. Lethal cancer types ultimately …

In the developing vertebrate embryo, segmentation initiates through the formation of repeated
segments, or somites, on either side of the posterior neural tube along the anterior to …

All vertebrates share a segmented body axis. Segments form from the rostral end of the
presomitic mesoderm ( PSM ) with a periodicity that is regulated by the segmentation clock. The …

Extra copies of centrosomes are frequently observed in cancer cells. To survive and
proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar …

Purpose Despite well‐informed work in several malignancies, the phenotypic effects of TP53
mutations in metastatic castration‐sensitive prostate cancer (mCSPC) progression and …

A striking example of coupling between growth and form occurs during the segmentation of
the vertebrate embryo. During segmentation, pairs of segments, one on either side of the …

Non-small cell lung carcinoma (NSCLC) is a major cause of cancer mortality. High
expression of the epithelial-to-mesenchymal transition transcription factor TWIST1 is strongly …

Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal cancer characterized by
very poor survival outcomes. Genomic sequencing of human PDAC tissues and cell lines …

In this study, we investigated the potential of TNIK inhibition as a radiosensitizing strategy in
lung squamous cell carcinoma (LSCC). LSCC is a type of lung malignancy that accounts for …

Small cell lung cancer (SCLC) is the most aggressive form of lung malignancies and accounts
for 15-20% of all lung cancers. It has the tendency to metastasize early, thus limited-stage …