User profiles for F. C. MacKintosh
Fred C MacKintoshRice University Verified email at rice.edu Cited by 30527 |
Modeling semiflexible polymer networks
CP Broedersz, FC MacKintosh - Reviews of Modern Physics, 2014 - APS
… CP Broedersz and FC MacKintosh: Modeling semiflexible … CP Broedersz and FC MacKintosh:
Modeling semiflexible … CP Broedersz and FC MacKintosh: Modeling semiflexible polymer …
Modeling semiflexible … CP Broedersz and FC MacKintosh: Modeling semiflexible polymer …
Microrheology
FC MacKintosh, CF Schmidt - Current opinion in colloid & interface science, 1999 - Elsevier
Several complementary techniques have been developed in recent years that make it possible
to measure viscoelastic properties of soft materials on micrometer scales. Such methods …
to measure viscoelastic properties of soft materials on micrometer scales. Such methods …
Intracellular transport by active diffusion
All substances exhibit constant random motion at the microscopic scale. This is a direct
consequence of thermal agitation, and leads to diffusion of molecules and small particles in a …
consequence of thermal agitation, and leads to diffusion of molecules and small particles in a …
Nonlinear elasticity in biological gels
C Storm, JJ Pastore, FC MacKintosh, TC Lubensky… - Nature, 2005 - nature.com
The mechanical properties of soft biological tissues are essential to their physiological function
and cannot easily be duplicated by synthetic materials. Unlike simple polymer gels, many …
and cannot easily be duplicated by synthetic materials. Unlike simple polymer gels, many …
Elastic behavior of cross-linked and bundled actin networks
Networks of cross-linked and bundled actin filaments are ubiquitous in the cellular cytoskeleton,
but their elasticity remains poorly understood. We show that these networks exhibit …
but their elasticity remains poorly understood. We show that these networks exhibit …
Elasticity of semiflexible biopolymer networks
We develop a model for cross-linked gels and sterically entangled solutions of semiflexible
biopolymers such as F-actin. Such networks play a crucial structural role in the cytoskeleton …
biopolymers such as F-actin. Such networks play a crucial structural role in the cytoskeleton …
Nonequilibrium mechanics of active cytoskeletal networks
Cells both actively generate and sensitively react to forces through their mechanical framework,
the cytoskeleton, which is a nonequilibrium composite material including polymers and …
the cytoskeleton, which is a nonequilibrium composite material including polymers and …
Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement
Cytoskeletal microtubules have been proposed to influence cell shape and mechanics
based on their ability to resist large-scale compressive forces exerted by the surrounding …
based on their ability to resist large-scale compressive forces exerted by the surrounding …
Tuning bilayer twist using chiral counterions
From seashells to DNA, chirality is expressed at every level of biological structures. In self-assembled
structures it may emerge cooperatively from chirality at the molecular scale. …
structures it may emerge cooperatively from chirality at the molecular scale. …
Scanning probe-based frequency-dependent microrheology of polymer gels and biological cells
A new scanning probe-based microrheology approach is used to quantify the frequency-dependent
viscoelastic behavior of both fibroblast cells and polymer gels. The scanning probe …
viscoelastic behavior of both fibroblast cells and polymer gels. The scanning probe …