User profiles for F. O. Vannberg

Dr. Fredrik O. Vannberg

Assistant Professor of Biology, Georgia Institute of Technology
Verified email at biology.gatech.edu
Cited by 17780

Human genetic susceptibility to intracellular pathogens

FO Vannberg, SJ Chapman, AVS Hill - Immunological reviews, 2011 - Wiley Online Library
Intracellular pathogens contribute to a significant proportion of infectious disease morbidity
and mortality worldwide. Increasing evidence points to a major role for host genetics in …

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

…, S Leslie, A Dilthey, P Ellis, C Langford, FO Vannberg… - Nature …, 2012 - nature.com
Trans-acting genetic variants have a substantial, albeit poorly characterized, role in the heritable
determination of gene expression. Using paired purified primary monocytes and B cells, …

A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

CC Khor, SJ Chapman, FO Vannberg, A Dunne… - Nature …, 2007 - nature.com
Toll-like receptors (TLRs) and members of their signaling pathway are important in the
initiation of the innate immune response to a wide variety of pathogens 1 , 2 , 3 . The adaptor …

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11. 2

T Thye, FO Vannberg, SH Wong, E Owusu-Dabo… - Nature …, 2010 - nature.com
We combined two tuberculosis genome-wide association studies from Ghana and The Gambia
with subsequent replication in a combined 11,425 individuals. rs4331426, located in a …

[HTML][HTML] Identifying recent adaptations in large-scale genomic data

…, RA Adegbola, RNK Bamezai, AVS Hill, FO Vannberg… - Cell, 2013 - cell.com
Although several hundred regions of the human genome harbor signals of positive natural
selection, few of the relevant adaptive traits and variants have been elucidated. Using full-…

Common variants at 11p13 are associated with susceptibility to tuberculosis

T Thye, E Owusu-Dabo, FO Vannberg, R Van Crevel… - Nature …, 2012 - nature.com
After imputation of data from the 1000 Genomes Project into a genome-wide dataset of
Ghanaian individuals with tuberculosis and controls, we identified a resistance locus on …

[HTML][HTML] Leprosy and the adaptation of human toll-like receptor 1

…, RNK Bamezai, AVS Hill, FO Vannberg - PLoS …, 2010 - journals.plos.org
Leprosy is an infectious disease caused by the obligate intracellular pathogen Mycobacterium
leprae and remains endemic in many parts of the world. Despite several major studies on …

[HTML][HTML] Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node

S Srinivasan, FO Vannberg, JB Dixon - Scientific reports, 2016 - nature.com
It is well documented that cells secrete exosomes, which can transfer biomolecules that impact
recipient cells’ functionality in a variety of physiologic and disease processes. The role of …

[HTML][HTML] CISH and Susceptibility to Infectious Diseases

CC Khor, FO Vannberg, SJ Chapman… - … England Journal of …, 2010 - Mass Medical Soc
Background The interleukin-2–mediated immune response is critical for host defense against
infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a …

[HTML][HTML] CD209 Genetic Polymorphism and Tuberculosis Disease

FO Vannberg, SJ Chapman, CC Khor, K Tosh, S Floyd… - PloS one, 2008 - journals.plos.org
Background Tuberculosis causes significant morbidity and mortality worldwide, especially
in sub-Saharan Africa. DC-SIGN, encoded by CD209, is a receptor capable of binding and …