User profiles for F. O. Vannberg
Dr. Fredrik O. VannbergAssistant Professor of Biology, Georgia Institute of Technology Verified email at biology.gatech.edu Cited by 17780 |
Human genetic susceptibility to intracellular pathogens
FO Vannberg, SJ Chapman, AVS Hill - Immunological reviews, 2011 - Wiley Online Library
Intracellular pathogens contribute to a significant proportion of infectious disease morbidity
and mortality worldwide. Increasing evidence points to a major role for host genetics in …
and mortality worldwide. Increasing evidence points to a major role for host genetics in …
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
…, S Leslie, A Dilthey, P Ellis, C Langford, FO Vannberg… - Nature …, 2012 - nature.com
Trans-acting genetic variants have a substantial, albeit poorly characterized, role in the heritable
determination of gene expression. Using paired purified primary monocytes and B cells, …
determination of gene expression. Using paired purified primary monocytes and B cells, …
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis
CC Khor, SJ Chapman, FO Vannberg, A Dunne… - Nature …, 2007 - nature.com
Toll-like receptors (TLRs) and members of their signaling pathway are important in the
initiation of the innate immune response to a wide variety of pathogens 1 , 2 , 3 . The adaptor …
initiation of the innate immune response to a wide variety of pathogens 1 , 2 , 3 . The adaptor …
Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11. 2
We combined two tuberculosis genome-wide association studies from Ghana and The Gambia
with subsequent replication in a combined 11,425 individuals. rs4331426, located in a …
with subsequent replication in a combined 11,425 individuals. rs4331426, located in a …
[HTML][HTML] Identifying recent adaptations in large-scale genomic data
…, RA Adegbola, RNK Bamezai, AVS Hill, FO Vannberg… - Cell, 2013 - cell.com
Although several hundred regions of the human genome harbor signals of positive natural
selection, few of the relevant adaptive traits and variants have been elucidated. Using full-…
selection, few of the relevant adaptive traits and variants have been elucidated. Using full-…
Common variants at 11p13 are associated with susceptibility to tuberculosis
After imputation of data from the 1000 Genomes Project into a genome-wide dataset of
Ghanaian individuals with tuberculosis and controls, we identified a resistance locus on …
Ghanaian individuals with tuberculosis and controls, we identified a resistance locus on …
[HTML][HTML] Leprosy and the adaptation of human toll-like receptor 1
…, RNK Bamezai, AVS Hill, FO Vannberg - PLoS …, 2010 - journals.plos.org
Leprosy is an infectious disease caused by the obligate intracellular pathogen Mycobacterium
leprae and remains endemic in many parts of the world. Despite several major studies on …
leprae and remains endemic in many parts of the world. Despite several major studies on …
[HTML][HTML] Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node
It is well documented that cells secrete exosomes, which can transfer biomolecules that impact
recipient cells’ functionality in a variety of physiologic and disease processes. The role of …
recipient cells’ functionality in a variety of physiologic and disease processes. The role of …
[HTML][HTML] CISH and Susceptibility to Infectious Diseases
CC Khor, FO Vannberg, SJ Chapman… - … England Journal of …, 2010 - Mass Medical Soc
Background The interleukin-2–mediated immune response is critical for host defense against
infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a …
infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a …
[HTML][HTML] CD209 Genetic Polymorphism and Tuberculosis Disease
FO Vannberg, SJ Chapman, CC Khor, K Tosh, S Floyd… - PloS one, 2008 - journals.plos.org
Background Tuberculosis causes significant morbidity and mortality worldwide, especially
in sub-Saharan Africa. DC-SIGN, encoded by CD209, is a receptor capable of binding and …
in sub-Saharan Africa. DC-SIGN, encoded by CD209, is a receptor capable of binding and …