Genetic studies of cardiometabolic traits
F Riveros Mckay Aguilera - 2019 - repository.cam.ac.uk
… Fernando Riveros Mckay Aguilera Churchill College University of … Fernando Riveros Mckay
Aguilera … , Ruklisa D, Mann AL, Mead D, Bouman H, RiverosMckay F, et al. (2016) The Allelic …
Aguilera … , Ruklisa D, Mann AL, Mead D, Bouman H, RiverosMckay F, et al. (2016) The Allelic …
[HTML][HTML] Associations of circulating C-reactive proteins, APOE ε4, and brain markers for Alzheimer's disease in healthy samples across the lifespan
The apolipoprotein E gene ε4 allele (APOE ε4) and higher circulating level of C-reactive
protein (CRP) have been extensively investigated as risk factors for Alzheimer’s disease (AD). …
protein (CRP) have been extensively investigated as risk factors for Alzheimer’s disease (AD). …
[HTML][HTML] Is periodontitis a risk factor for ischaemic stroke, coronary artery disease and subclinical atherosclerosis? A Mendelian randomization study
Background and aims Observational studies have reported an association between
periodontitis and cardiovascular disease but whether this association is causal is uncertain. We …
periodontitis and cardiovascular disease but whether this association is causal is uncertain. We …
[HTML][HTML] Evaluating the impact of modeling choices on the performance of integrated genetic and clinical models
The value of genetic information for improving the performance of clinical risk prediction
models has yielded variable conclusions. Many methodological decisions have the potential to …
models has yielded variable conclusions. Many methodological decisions have the potential to …
Combining clinical and polygenic risk improves stroke prediction among individuals with atrial fibrillation
Background Atrial fibrillation (AF) is associated with a five-fold increased risk of ischemic
stroke. A portion of this risk is heritable, however current risk stratification tools (CHA2DS2-VASc…
stroke. A portion of this risk is heritable, however current risk stratification tools (CHA2DS2-VASc…
[HTML][HTML] Sortilin as a biomarker for cardiovascular disease revisited
Genetic variants in the genomic region containing SORT1 (encoding the protein sortilin) are
strongly associated with cholesterol levels and the risk of coronary artery disease (CAD). …
strongly associated with cholesterol levels and the risk of coronary artery disease (CAD). …
43rd European Mathematical Genetics Meeting (EMGM) 2015
E Génin, K Rouault - Human Heredity, 2015 - JSTOR
Many novel associations between genetic variants and human disease have been successfully
identified using genome-wide association studies (GWAS). However, a typical GWAS …
identified using genome-wide association studies (GWAS). However, a typical GWAS …
Functional genomic studies of cancer immune evasion using in vitro and in vivo CRISPR/Cas9 genetic screens
DA Garyfallos - 2021 - repository.cam.ac.uk
… Thanks to Fernando Riveros Mckay Aguilera, for his amazing friendship, icebreaking sense
of humour, inventive name inversions, and pop culture references. I would also like to say …
of humour, inventive name inversions, and pop culture references. I would also like to say …
[HTML][HTML] Genome-wide association studies of COVID-19: Connecting the dots
LC Ferreira, CEM Gomes, JF Rodrigues-Neto… - Infection, Genetics and …, 2022 - Elsevier
Genome-wide association studies (GWASs) are a research approach used to identify genetic
variants associated with common diseases, like COVID-19. The lead genetic variants (n = …
variants associated with common diseases, like COVID-19. The lead genetic variants (n = …
Applying animal modelling to understand rare novel neurodevelopmental disorders associated with intellectual disability
M Levitin - 2019 - repository.cam.ac.uk
Intellectual disability (ID) is categorised by a significant reduction in cognitive function and
adaptive abilities that begin in childhood. ID is part of a heterogeneous group of …
adaptive abilities that begin in childhood. ID is part of a heterogeneous group of …