[HTML][HTML] Integrative microbiomics in bronchiectasis exacerbations
…, HR Keir, AJ Dicker, KX Thng, A Tsang, FX Ivan… - Nature medicine, 2021 - nature.com
Bronchiectasis, a progressive chronic airway disease, is characterized by microbial colonization
and infection. We present an approach to the multi-biome that integrates bacterial, viral …
and infection. We present an approach to the multi-biome that integrates bacterial, viral …
[HTML][HTML] The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi
LLY Chan, DE Anderson, HS Cheng, FX Ivan… - Nature …, 2022 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and
infective exacerbations, however, in-vitro model systems for the study of host-pathogen …
infective exacerbations, however, in-vitro model systems for the study of host-pathogen …
Microbial dysregulation of the gut-lung axis in bronchiectasis
…, TK Jaggi, NABM Ali, FX Ivan… - American Journal of …, 2023 - atsjournals.org
Rationale: Emerging data support the existence of a microbial “gut-lung” axis that remains
unexplored in bronchiectasis. Methods: Prospective and concurrent sampling of gut (stool) …
unexplored in bronchiectasis. Methods: Prospective and concurrent sampling of gut (stool) …
[HTML][HTML] Environmental fungal sensitisation associates with poorer clinical outcomes in COPD
…, M Mac Aogáin, TK Jaggi, FX Ivan… - European …, 2020 - Eur Respiratory Soc
… , Tavleen Kaur Jaggi, Fransiskus Xaverius Ivan, Nicolas E. Gaultier, … FX Ivan and M. Mac
Aogain: data interpretation, bioinformatics … Conflict of interest: FX Ivan has nothing to disclose. …
Aogain: data interpretation, bioinformatics … Conflict of interest: FX Ivan has nothing to disclose. …
[HTML][HTML] Peptide-based subunit vaccine design of T-and B-cells multi-epitopes against Zika virus using immunoinformatics approaches
…, K Grazzolie, R Rosmalena, F Yazid, FX Ivan… - Microorganisms, 2019 - mdpi.com
The Zika virus disease, also known as Zika fever is an arboviral disease that became epidemic
in the Pacific Islands and had spread to 18 territories of the Americas in 2016. Zika virus …
in the Pacific Islands and had spread to 18 territories of the Americas in 2016. Zika virus …
Structure-based discovery of novel inhibitors of Mycobacterium tuberculosis CYP121 from Indonesian natural products
VD Prasasty, S Cindana, FX Ivan, H Zahroh… - … Biology and Chemistry, 2020 - Elsevier
Tuberculosis (TB) continues to be a serious global health threat with the emergence of
multidrug-resistant tuberculosis (MDR-TB) and extremely drug-resistant tuberculosis (XDR-TB). …
multidrug-resistant tuberculosis (MDR-TB) and extremely drug-resistant tuberculosis (XDR-TB). …
Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation
A Versi, FX Ivan, MI Abdel‐Aziz, S Bates, J Riley… - Allergy, 2023 - Wiley Online Library
… Ali Versi and Fransiskus Xaverius Ivan contributed equally to this study. … Dr Montuschi,
Dr Kermani, Dr Adcock, Dr Ivan, Dr Abdel-Aziz and Mr Versi have nothing to declare. …
Dr Kermani, Dr Adcock, Dr Ivan, Dr Abdel-Aziz and Mr Versi have nothing to declare. …
[HTML][HTML] Neutrophils infected with highly virulent influenza H3N2 virus exhibit augmented early cell death and rapid induction of type I interferon signaling pathways
FX Ivan, KS Tan, MC Phoon, BP Engelward… - Genomics, 2013 - Elsevier
We developed a model of influenza virus infection of neutrophils by inducing differentiation
of the MPRO promyelocytic cell line. After 5days of differentiation, about 20–30% of mature …
of the MPRO promyelocytic cell line. After 5days of differentiation, about 20–30% of mature …
Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling …
FX Ivan, JC Rajapakse, RE Welsch, SG Rozen… - Functional & integrative …, 2012 - Springer
Investigating the relationships between critical influenza viral mutations contributing to
increased virulence and host expression factors will shed light on the process of severe …
increased virulence and host expression factors will shed light on the process of severe …
The healthy airway mycobiome in individuals of Asian descent
NABM Ali, FX Ivan, M Mac Aogáin, JK Narayana… - Chest, 2021 - journal.chestnet.org
Results Key airway fungi within a healthy mycobiome are illustrated in Figure 1 B and
consist of Ascomycota (93.0%) and Basidiomycota (7.0%). The main fungal genera include …
consist of Ascomycota (93.0%) and Basidiomycota (7.0%). The main fungal genera include …