User profiles for F. Brosseron
Frederic BrosseronDZNE Bonn, Germany Verified email at dzne.de Cited by 9162 |
Neuroinflammation in Alzheimer's disease
…, J El Khoury, GE Landreth, F Brosseron… - The Lancet …, 2015 - thelancet.com
Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the
neuronal compartment, but includes strong interactions with immunological mechanisms in …
neuronal compartment, but includes strong interactions with immunological mechanisms in …
[HTML][HTML] Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview
F Brosseron, M Krauthausen, M Kummer… - Molecular …, 2014 - Springer
This article gives a comprehensive overview of cytokine and other inflammation associated
protein levels in plasma, serum and cerebrospinal fluid (CSF) of patients with Alzheimer’s …
protein levels in plasma, serum and cerebrospinal fluid (CSF) of patients with Alzheimer’s …
NLRP3 inflammasome activation drives tau pathology
…, D Tejera, A Griep, F Santarelli, F Brosseron… - Nature, 2019 - nature.com
… f, Quantification of time spent in quadrant 1 (Q1) versus all other quadrants (ao) at probe trial
… f, IL-1β levels in conditioned medium of primary wild-type microglia treated with LPS and 10 …
… f, IL-1β levels in conditioned medium of primary wild-type microglia treated with LPS and 10 …
sTREM 2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
…, L Rami, JL Molinuevo, F Brosseron… - EMBO molecular …, 2016 - embopress.org
… sTREM2 were not significantly affected by gender (F 1,521 … that CSF sTREM2 levels differed
between groups (F 2,242 … levels of CSF sTREM2 differed within these three groups (F 2,349 …
between groups (F 2,242 … levels of CSF sTREM2 differed within these three groups (F 2,349 …
Basal forebrain atrophy along the Alzheimer's disease spectrum and its relevance for subjective cognitive decline
Background There is growing evidence in the literature that the cholinergic basal forebrain
might be one of the earliest affected structures in Alzheimer’s disease (AD). Recent data …
might be one of the earliest affected structures in Alzheimer’s disease (AD). Recent data …
Mediterranean diet, Alzheimer disease biomarkers, and brain atrophy in old age
…, A Schröder, S Wolfsgruber, S Altenstein, F Brosseron… - Neurology, 2021 - AAN Enterprises
Objective To determine whether following a Mediterranean-like diet (MeDi) relates to
cognitive functions and in vivo biomarkers for Alzheimer disease (AD), we analyzed cross-sectional …
cognitive functions and in vivo biomarkers for Alzheimer disease (AD), we analyzed cross-sectional …
[HTML][HTML] Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE)
… We report the statistics for the overall group effect (F-statistic/omnibus chi-square test with p
value) and indicate significant single contrasts of each group compared to the control group, …
value) and indicate significant single contrasts of each group compared to the control group, …
Instruments and methods in proteomics
C May, F Brosseron, P Chartowski… - Data Mining in …, 2011 - Springer
In the past decade, major developments in instrumentation and methodology have been
achieved in proteomics. For proteome investigations of complex biological samples derived …
achieved in proteomics. For proteome investigations of complex biological samples derived …
Soluble Aβ oligomers and protofibrils induce NLRP3 inflammasome activation in microglia
…, I Dalgėdienė, S Schwartz, F Brosseron… - Journal of …, 2020 - Wiley Online Library
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder causing
memory loss, language problems and behavioural disturbances. AD is associated with the …
memory loss, language problems and behavioural disturbances. AD is associated with the …
[HTML][HTML] Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study
…, P Kalbhen, MT Heneka, F Brosseron… - Alzheimer's research & …, 2019 - Springer
Background Subjective cognitive decline (SCD) has been proposed as a pre-MCI at-risk
condition of Alzheimer’s disease (AD). Current research is focusing on a refined assessment of …
condition of Alzheimer’s disease (AD). Current research is focusing on a refined assessment of …