Millions of people worldwide suffer from trauma- or age-related orthopedic diseases such as
osteoarthritis, osteoporosis, or cancer. Tissue Engineering (TE) and Regenerative Medicine …

An integral approach toward in situ tissue engineering through scaffolds that mimic tissue
with regard to both tissue architecture and biochemical composition is presented. Monolithic …

Introduction One common cause of disability in modern society is low back pain. The main
reason for this pain is the degeneration of the intervertebral disc (IVD), particularly of the …

There is a great need for valuable ex vivo models that allow for assessment of cartilage repair
strategies to reduce the high number of animal experiments. In this paper we present three …

… This is the value of n which gives f F K = f d , the threshold value of f above which differentiation
occurs. This value of f FK is associated with a threshold value of a F K = a d , and from …

… Imaging was done using a Jeol JSM-6335 F field emission scanning electron microscope
at … Genipin crosslinked scaffolds had a large amount of background signal in (f) and (g). The …

… Hatched areas represent values obtained from analysis of CERASORB® M (F).
Background level of extraction solution is illustrated by dotted horizontal line (E; F). Statistical …

The development of scaffold formulations based on extracellular matrix (ECM)-inspired
synthetic materials constitutes an important resource for the advance of cell-based therapies in …

… = 0 otherwise), so that differentiation is active when f > f d . The use of a step function here is
… 1 represents the rate at which MSCs differentiate when f > f d ; a representative value of this …

For many tissue engineering applications, cells such as human mesenchymal stem cells (hMSCs)
must be embedded in hydrogels. The analysis of embedded hMSCs requires RNA …