User profiles for F. Gonzalez

Frank J. Gonzalez

National Cancer Institute
Verified email at mail.nih.gov
Cited by 190979

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

…, RW Estabrook, R Feyereisen, FJ Gonzalez… - DNA and cell …, 1993 - liebertpub.com
We provide here a list of 221 P450 genes and 12 putative pseudogenes that have been
characterized as of December 14, 1992. These genes have been described in 31 eukaryotes (…

P450 genes: structure, evolution, and regulation

DW Nebert, FJ Gonzalez - Annual review of biochemistry, 1987 - annualreviews.org
Cytochromes P450 are enzymes involved in the oxidative metabolism of steroids, fatty acids,
prostaglandins, leukotrienes, biogenic amines, pher omones, and plant metabolites. These …

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature

…, Y FUJII-KURIYAMA, FJ GONZALEZ… - DNA and cell …, 1991 - liebertpub.com
We provide here a list of 154 P450 genes and seven putative pseudogenes that have been
characterized as of October 20, 1990. These genes have been described in a total of 23 …

Anxiety, depression, and asthma control: changes after standardized treatment

…, M Rial, V Plaza, FC González… - The Journal of Allergy …, 2018 - Elsevier
Background It has been documented that anxiety and depression are prevalent in patients
with asthma and are associated with greater frequency of exacerbations, increased use of …

[PDF][PDF] Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis

…, M Miyata, JM Ward, G Lambert, FJ Gonzalez - Cell, 2000 - cell.com
… (E) Fecal and (F) urinary BA excretion rate of control or fed mice. Data are mean … /BAR null
mice (D and F) fed a control (C and D) or 1% cholesterol (E and F) diet for 28 days. Vacuoles …

[HTML][HTML] Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

…, J Seydoux, JM Peters, FJ Gonzalez… - The Journal of …, 1999 - Am Soc Clin Investig
Prolonged deprivation of food induces dramatic changes in mammalian metabolism,
including the release of large amounts of fatty acids from the adipose tissue, followed by their …

Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome …

…, H Westphal, FJ Gonzalez - … and cellular biology, 1995 - Taylor & Francis
To gain insight into the function of peroxisome proliferator-activated receptor (PPAR)
isoforms in rodents, we disrupted the ligand-binding domain of the α isoform of mouse PPAR (…

[HTML][HTML] Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

…, YS Tan, JH Baek, JB Wesley, FJ Gonzalez… - Journal of Biological …, 2008 - ASBMB
… This article has been withdrawn by the authors, except F. Gonzalez who did not agree to
this withdrawal notice, and JB Wesley who could not be reached. The withdrawing authors and …

[HTML][HTML] High versus low blood-pressure target in patients with septic shock

…, F Gonzalez, C Guitton, F Tamion… - … England Journal of …, 2014 - Mass Medical Soc
Background The Surviving Sepsis Campaign recommends targeting a mean arterial pressure
of at least 65 mm Hg during initial resuscitation of patients with septic shock. However, …

[HTML][HTML] Social capital I: measurement and associations with economic mobility

…, N Hendren, RB Fluegge, S Gong, F Gonzalez… - Nature, 2022 - nature.com
… To obtain measures of the degree of homophily that are not sensitive to the size of each
quantile bin, we normalize f Q,i by the share of individuals in the sample who belong to quantile …