Aims Atrial fibrillation (AF) is the most common type of arrhythmia in humans, yet the genetic
cause of AF remains elusive. Genome-wide association studies (GWASs) have reported risk …

The unconventional prefoldin URI/RMP, in humans, and its orthologue in yeast, Bud27, have
been proposed to participate in the biogenesis of the RNA polymerases. However, this role …

Myotonic dystrophy type 1 (DM1) is caused by the expansion of CTG repeats in the 3′
untranslated region of the DMPK gene. Several missplicing events and transcriptional alterations …

Skeletal muscle is a heterogeneous tissue that represents between 30 and 38% of the
human body mass and has important functions in the organism, such as maintaining posture, …

Cardiovascular development is a complex developmental process in which multiple cell
lineages are involved, namely the deployment of first and second heart fields. Beside the …

… Esteban performed data analysis and interpretation; Chris Doherty collected and/or
assembled data; Francisco Hernández-Torres collected and/or assembled data; Diego Franco …

Aims: A three-step catalytic cycle is common to all peroxiredoxins (Prxs), despite structural
and kinetic differences. The second step in 1-Cys type Prxs is a matter of debate since they …

Pitx2 is a paired-related homeobox gene that is expressed in muscle progenitors during
myogenesis. We have previously demonstrated that overexpression of Pitx2c isoform in …

Muscle regeneration is an important homeostatic process of adult skeletal muscle that
recapitulates many aspects of embryonic myogenesis. Satellite cells (SCs) are the main muscle …

Spontaneous self-terminating atrial fibrillation (AF) is one of the most common heart rhythm
disorders, yet the regulatory molecular mechanisms underlying this syndrome are rather …