The ability to simultaneously genotype hundreds of thousands of single‐nucleotide
polymorphisms (SNPs) in a single assay has recently become feasible due to innovative …

We have developed an array‐based whole‐genome genotyping (WGG) assay (Infinium) using
our BeadChip platform that effectively enables unlimited multiplexing and unconstrained …

… The remaining 17% of SNPs (A/T and C/G) can be assayed by Infinium I assays, and by
using SBE biochemistry as described by Steemers and colleagues, both assays can be run …

Mammalian organogenesis is a remarkable process. Within a short timeframe, the cells of
the three germ layers transform into an embryo that includes most of the major internal and …

To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile
the transcriptomes of single cells or nuclei, termed sci-RNA-seq (single-cell combinatorial …

Technical advances have enabled the collection of genome and transcriptome data sets
with single-cell resolution. However, single-cell characterization of the epigenome has …

INTRODUCTION A reference atlas of human cell types is a major goal for the field. Here, we
set out to generate single-cell atlases of both gene expression (this study) and chromatin …

Oligonucleotide probe arrays have enabled massively parallel analysis of gene expression
levels from a single cDNA sample. Application of microarray technology to analyzing …

The synthesis is described of a series of calix [4] arenes with three different sensitizer
chromophores (“antenna”) attachedto the lower rim via a short spacer. In the Eu3+ and Tb3+ …

Although we can increasingly measure transcription, chromatin, methylation, and other
aspects of molecular biology at single-cell resolution, most assays survey only one aspect of …