Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice
F Pan-Montojo, O Anichtchik, Y Dening, L Knells… - Nature …, 2010 - nature.com
… Competing interests: Francisco Pan-Montojo has a patent application pending for this
animal model (Application number PCT/EP 2009/005688). This does not alter the author’s …
animal model (Application number PCT/EP 2009/005688). This does not alter the author’s …
[HTML][HTML] Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease
…, J Levin, S Shi, F Schmidt, C Prix, F Pan-Montojo… - Acta …, 2013 - Springer
In neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD)
and prion diseases, deposits of aggregated disease-specific proteins are found. Oligomeric …
and prion diseases, deposits of aggregated disease-specific proteins are found. Oligomeric …
[HTML][HTML] Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice
F Pan-Montojo, M Schwarz, C Winkler, M Arnhold… - Scientific reports, 2012 - nature.com
Pathological studies on Parkinson's disease (PD) patients suggest that PD pathology
progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous …
progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous …
[HTML][HTML] Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
…, J Sterneckert, M Frickenhaus, F Pan-Montojo… - Nature …, 2018 - nature.com
… f–i Quantification of e and in addition at 110 DIV, f distal axon integrity (% fragmented
SMI32-positive axons), g % NeuN-positive Hoechst nuclei, h % SMI32-positive NeuN cells and i % …
SMI32-positive axons), g % NeuN-positive Hoechst nuclei, h % SMI32-positive NeuN cells and i % …
[HTML][HTML] Considerations on the role of environmental toxins in idiopathic Parkinson's disease pathophysiology
F Pan-Montojo, H Reichmann - Translational neurodegeneration, 2014 - Springer
Neurodegenerative diseases are characterized by a progressive dysfunction of the nervous
system. Often associated with atrophy of the affected central or peripheral nervous structures…
system. Often associated with atrophy of the affected central or peripheral nervous structures…
Cuminaldehyde as the Major Component of Cuminum cyminum, a Natural Aldehyde with Inhibitory Effect on Alpha‐Synuclein Fibrillation and Cytotoxicity
…, A Fassihi, F Pan‐Montojo… - Journal of food …, 2015 - Wiley Online Library
… and ROS assessing), Amir Tayaranian did site direct mutations and protein labeling,
Afshin Fassihi and Horacio Pérez-Sánchez helped in structural studies, Francisco Pan-Montojo …
Afshin Fassihi and Horacio Pérez-Sánchez helped in structural studies, Francisco Pan-Montojo …
[HTML][HTML] Baicalein inhibits α-synuclein oligomer formation and prevents progression of α-synuclein accumulation in a rotenone mouse model of Parkinson's disease
…, H Jiang, A Liu, C Zhang, F Pan-Montojo… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disease. α-Synuclein (α-syn)
oligomers play a critical role in the progression of PD. Baicalein, a typical flavonoid …
oligomers play a critical role in the progression of PD. Baicalein, a typical flavonoid …
[HTML][HTML] Long-term kinetics of Zika virus RNA and antibodies in body fluids of a vasectomized traveller returning from Martinique: a case report
…, L Zoeller, M Trottmann, F Pan-Montojo… - BMC infectious …, 2017 - Springer
… Briefly, fragments of 772 base pairs and 345 nucleotides size were amplified from the
extracted nucleic acid using the primers Z4360 F 5′- CTCTgTACACTCCATCTgTggTC-3′ and …
extracted nucleic acid using the primers Z4360 F 5′- CTCTgTACACTCCATCTgTggTC-3′ and …
Phenotypes and malignancy risk of different FUS mutations in genetic amyotrophic lateral sclerosis
…, V Danel, P Corcia, F Pan‐Montojo… - Annals of clinical …, 2019 - Wiley Online Library
Objective Mutations in Fused in Sarcoma (FUS or TLS) are the fourth most prevalent in
Western European familial amyotrophic lateral sclerosis (ALS) populations and have been …
Western European familial amyotrophic lateral sclerosis (ALS) populations and have been …
Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival
Parkinson's disease is associated with mitochondrial decline in dopaminergic neurons of
the substantia nigra. One of the genes linked with the onset of Parkinson's disease, DJ-1/…
the substantia nigra. One of the genes linked with the onset of Parkinson's disease, DJ-1/…