Abstract Changes in promoter structure and occupation have been shown to modify the
splicing pattern of several genes, evidencing a coupling between transcription and alternative …

Alternative splicing of messenger RNA precursors is an extraordinary source of protein
diversity and the regulation of this process is crucial for diverse cellular functions in both …

DNA damage induces apoptosis and many apoptotic genes are regulated via alternative
splicing (AS), but little is known about the control mechanisms. Here we show that ultraviolet …

Serine/arginine-rich (SR) proteins are important regulators of mRNA splicing. Several
postsplicing activities have been described for a subset of shuttling SR proteins, including …

In search for physiological pathways affecting alternative splicing through its kinetic coupling
with transcription, we found that membrane depolarization of neuronal cells triggers the …

The roles of Argonaute proteins in cytoplasmic microRNA and RNAi pathways are well
established. However, their implication in small RNA-mediated transcriptional gene silencing in …

Heterogeneous nuclear ribonucleoprotein (hnRNP) K is a nucleocytoplasmic shuttling protein
that is a key player in the p53-triggered DNA damage response, acting as a cofactor for …

… Additionally, a fragment containing the two predicted high-affinity SIMs in GEI-17 (aa 423–602
in isoform f), pulled down higher molecular weight forms of both sumoylated GEI-17 and …

… Federico Pelisch… F. Pelisch and A. Srebrow are career investigators of the CONICET. We
apologize to colleagues whose interesting work could not be cited due to space limitations. …

Protein modification by conjugation of small ubiquitin-related modifier (SUMO) is involved in
diverse biological functions, such as transcription regulation, subcellular partitioning, stress …