HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals

…, C Blé, F Meacci, S Ruzzante, A Salvi, F Semplici… - Nature medicine, 1997 - nature.com
HIV-specific mucosal and cellular immunity was analyzed in heterosexual couples discordant
for HIV status in serum and in HIV-unexposed controls. HIV-specific IgA but not IgG was …

[PDF][PDF] Beta cell hubs dictate pancreatic islet responses to glucose

…, RK Mitchell, E Haythorne, MP Pessoa, F Semplici… - Cell metabolism, 2016 - cell.com
… (D–F) Representative functional connectivity map and activity plots at high glucose (11 mM),
before (D), during (E) and after (F… (E and F) Cytokine alters the distribution of correlated links …

[HTML][HTML] The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells

AI Tarasov, F Semplici, MA Ravier, EA Bellomo… - PloS one, 2012 - journals.plos.org
… The data are expressed as (FF FCCP )/(F 0 -F FCCP ), where F 0 and F FCCP represent
TMRE fluorescence intensity in 3 mM glucose and 2 µM FCCP, respectively. *Differences are …

ADCY5 couples glucose to insulin secretion in human islets

…, L Marselli, TJ Pullen, S Gimeno Brias, F Semplici… - Diabetes, 2014 - Am Diabetes Assoc
F: Summary statistics demonstrate similar effects of GLP-1 on ATP/ADP in islets exposed
to 3 or 17 mmol/L glucose (NS, nonsignificant vs. Con; Mann-Whitney U test; n = 10–13 …

Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV-seropositive persons

…, D Trabattoni, SL Caputo, F Semplici… - The Journal of …, 1999 - academic.oup.com
The presence and activity of human immunodeficiency virus (HIV)—specific antibodies were
analyzed in the sera of 15 sexually exposed seronegative persons who had systemic HIV-…

[HTML][HTML] Protein kinase CK2α′ is induced by serum as a delayed early gene and cooperates with Ha-ras in fibroblast transformation

M Orlandini, F Semplici, R Ferruzzi, F Meggio… - Journal of Biological …, 1998 - ASBMB
Protein kinase CK2 is an ubiquitous and pleiotropic Ser/Thr protein kinase composed of two
catalytic (α and/or α′) and two noncatalytic (β) subunits forming a heterotetrameric …

[HTML][HTML] Frequency-dependent mitochondrial Ca2+ accumulation regulates ATP synthesis in pancreatic β cells

AI Tarasov, F Semplici, D Li, R Rizzuto… - … -European Journal of …, 2013 - Springer
… For example, in the case of [Ca 2+ ] mit , ∼4 bursts min −1 were required to achieve 80 %
F/F max . By contrast, the same F/F max was obtained for [Ca 2+ ] cyt . with a burst frequency of …

[HTML][HTML] The pore-forming subunit MCU of the mitochondrial Ca2+ uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice

…, SPX Davis, A Martinez-Sanchez, F Semplici… - Diabetologia, 2020 - Springer
… Traces represent mean normalised fluorescence intensity over time (F/F min ), where F min
is the mean fluorescence recorded at the end of the application of FCCP. Delta psi (Δ psi ) is …

Chlamydia pneumoniae antibody response in patients with acute myocardial infarction and their follow-up

S Mazzoli, N Tofani, A Fantini, F Semplici, F Bandini… - American heart …, 1998 - Elsevier
Study Populations This study concerned the possible relations between seroreactivity to
Chlamydia pneumoniae and myocardial infarction. A group of 29 patients with acute myocardial …

CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with β-TrCP and enhances β-catenin degradation

F Semplici, F Meggio, LA Pinna, S Oliviero - Oncogene, 2002 - nature.com
… Following CK2-dependent phosphorylation both UBC3B and UBC3 bind to the F-box protein
β-TrCP, the substrate recognition subunit of an SCF (Skp1, Cul1, F-box) ubiquitin ligase. …