Every optical imaging technique is limited in its penetration depth by scattering occurring in
biological tissues. Possible solutions to overcome this problem consist of limiting the …

… f,g) Three-dimensional tracing of single neurons through different stacks and layers of the
hippocampus. Image in f … (c,d,e,f) High resolution insert of stack corresponding to red boxes in c…

… (a) A constant force F tot = ΔF is applied to DNA suspended between the 2OTs through two
feedback systems clamping the force on the left and right bead to −F and F + ΔF, respectively. …

The mechanism of the denaturing effects of urea and the guanidinium ion on proteins is still
an unsolved and important problem in protein chemistry. Changes in the hydrogen bond …

… Figure 3e–f highlights a large variability in the responsiveness of different tubular
elements to the propagation of AP. Even though the tubules are connected to the surface, AP …

… principle of our method illustrating constant F tot = ΔF applied to molecule B through two
feedback systems clamping the force on the left and right bead to −F and F + ΔF, respectively. …

Understanding of complex biological processes requires knowledge of molecular structures
and measurement of their dynamics in vivo. The collective chemomechanical action of …

… the ΔF/F 0 peak amplitude and frequencies measured upon treatment with this drug were
not distinguishable from the control levels. The linear response observed for the ΔF/F 0 signal …

The tethered particle motion (TPM) allows the direct detection of activity of a variety of
biomolecules at the single molecule level. First pioneered for RNA polymerase, it has recently …

The ribosome is universally responsible for synthesizing proteins by translating the genetic
code transcribed in mRNA into an amino acid sequence. Ribosomes use cellular accessory …