Drug treatment of epilepsy is characterized by unpredictability of efficacy, adverse drug
reactions, and optimal doses in individual patients, which, at least in part, is a consequence of …

Myasthenia gravis (MG) is an autoimmune antibody-mediated disorder of neuromuscular
synaptic transmission. The clinical hallmark of MG consists of fluctuating fatigability and …

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

To identify rare causal variants in late-onset Parkinson disease (PD), we investigated an
Austrian family with 16 affected individuals by exome sequencing. We found a missense …

We identified 15q13.3 microdeletions encompassing the CHRNA7 gene in 12 of 1,223
individuals with idiopathic generalized epilepsy (IGE), which were not detected in 3,699 controls (…

Idiopathic generalized epilepsies account for 30% of all epilepsies. Despite a predominant
genetic aetiology, the genetic factors predisposing to idiopathic generalized epilepsies …

Idiopathic focal epilepsy (IFE) with rolandic spikes is the most common childhood epilepsy,
comprising a phenotypic spectrum from rolandic epilepsy (also benign epilepsy with …

A panel of 13 monoclonal antibodies (mAbs) has been raised to the central nervous system-specific
glycoprotein, myelin oligodendrocyte glycoprotein; five of these mAbs recognize a …

… Pair-wise F st values between samples were calculated using EIGENSOFT. F st values …
In our study, F st was found to correlate considerably with geographic distances (r 2 = 0.382, …

Many common illnesses, for reasons that have not been identified, differentially affect men
and women. For instance, the autoimmune diseases systemic lupus erythematosus (SLE) and …