Many mitochondrial proteins are synthesized with N-terminal presequences that are removed
by specific peptidases. The N-termini of the mature proteins and thus peptidase cleavage …

The terminal enzyme of the mitochondrial respiratory chain, cytochrome oxidase, transfers
electrons to molecular oxygen, generating water. Within the inner mitochondrial membrane, …

Most mitochondrial proteins possess N-terminal presequences that are required for
targeting and import into the organelle. Upon import, presequences are cleaved off by matrix …

Elucidating the biology of yeast in its full complexity has major implications for science, medicine
and industry. One of the most critical processes determining yeast life and physiology is …

Mitochondrial proteins are synthesized as precursor proteins on either cytosolic or mitochondrial
ribosomes. The synthesized precursors from both translation origins possess targeting …

The intermembrane space (IMS) represents the smallest subcompartment of mitochondria.
Nevertheless, it plays important roles in the transport and modification of proteins, lipids, and …

Mitochondrial outer membrane permeabilization is a watershed event in the process of
apoptosis, which is tightly regulated by a series of pro‐ and anti‐apoptotic proteins belonging to …

The mitochondrial proteome comprises ~1000 (yeast)–1500 (human) different proteins, which
are distributed into four different subcompartments. The sublocalization of these proteins …

Most mitochondrial proteins are encoded in the nucleus as precursor proteins and carry N-terminal
presequences for import into the organelle. The vast majority of presequences are …

Biogenesis of complex IV of the mitochondrial respiratory chain requires assembly factors
for subunit maturation, co-factor attachment and stabilization of intermediate assemblies. A …