The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus, coxsackieviruses,
echoviruses, numbered enteroviruses and rhinoviruses. These diverse viruses cause a …

The Enterovirus (EV) and Parechovirus genera of the picornavirus family include many
important human pathogens, including poliovirus, rhinovirus, EV-A71, EV-D68, and human …

… We thank Bas Kolpa and Gilbert van Hagen from the veterinary practice De Oosthof for
their help in acquiring the Dutch PEDV-UU isolate. We are indebted to the National Natural …

The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused
a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted …

Many RNA viruses remodel intracellular membranes to generate specialized sites for RNA
replication. How membranes are remodeled and what properties make them conducive for …

Human betacoronaviruses OC43 and HKU1 are endemic respiratory pathogens and, while
related, originated from independent zoonotic introductions. OC43 is in fact a host-range …

The coronavirus spike glycoprotein, located on the virion surface, is the key mediator of cell
entry and the focus for development of protective antibodies and vaccines. Structural studies …

Digital‐imaging microscopy was performed to study the effect of Coxsackie B3 virus
infection on the cytosolic free Ca 2+ concentration and the Ca 2+ content of the endoplasmic …

… We thank Herman Egberink and Floor van der Vegt for technical assistance. We thank
Monique Spronken and Debby van Riel (Department of Viroscience, Erasmus Medical Center) for …

RIG-I and MDA5 are cytosolic RNA sensors that play a critical role in innate antiviral responses.
Major advances have been made in identifying RIG-I ligands, but our knowledge of the …