User profiles for F.X Real

Francisco X Real

Senior Group Leader, CNIO, Madrid; Professor of Cell Biology, Universitat Pompeu Fabra …
Verified email at cnio.es
Cited by 34599

[HTML][HTML] Addressing the challenges of pancreatic cancer: future directions for improving outcomes

…, R Labianca, JM Löhr, J Neoptolemos, FX Real… - Pancreatology, 2015 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC), which accounts for more than 90% of all pancreatic
tumours, is a devastating malignancy with an extremely poor prognosis, as shown by a 1…

P53 as a prognostic marker for bladder cancer: a meta-analysis and review

…, M Rivas, D Puente, M Kogevinas, FX Real - The lancet …, 2005 - thelancet.com
Background P53 is the most widely investigated molecular marker in bladder cancer. We
aimed to review comprehensively the evidence for use of changes in P53 to predict bladder-…

Epidemiology of urinary bladder cancer: from tumor development to patient's death

…, MP Zeegers, G Steineck, M Kogevinas, FX Real… - World journal of …, 2007 - Springer
Urinary bladder cancer (UBC) ranks ninth in worldwide cancer incidence. It is more frequent
in men than in women. We review the main established/proposed factors, both …

[HTML][HTML] A consensus molecular classification of muscle-invasive bladder cancer

…, PC Black, L Dyrskjøt, M Höglund, SP Lerner, FX Real… - European urology, 2020 - Elsevier
Background Muscle-invasive bladder cancer (MIBC) is a molecularly diverse disease with
heterogeneous clinical outcomes. Several molecular classifications have been proposed, but …

NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses

…, C Samanic, M Torà, F Fernández, FX Real… - The Lancet, 2005 - thelancet.com
Background Many reported associations between common genetic polymorphisms and
complex diseases have not been confirmed in subsequent studies. An exception could be the …

Bladder cancer and exposure to water disinfection by-products through ingestion, bathing, showering, and swimming in pools

…, R Marcos, N Rothman, FX Real… - American journal of …, 2007 - academic.oup.com
Bladder cancer has been associated with exposure to chlorination by-products in drinking
water, and experimental evidence suggests that exposure also occurs through inhalation and …

[PDF][PDF] Comprehensive transcriptional analysis of early-stage urothelial carcinoma

…, JS Pedersen, PU Malmström, N Malats, FX Real… - Cancer cell, 2016 - cell.com
Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease with widely
different outcomes. We performed a comprehensive transcriptional analysis of 460 early-stage …

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

…, G Zogopoulos, JMS Bartlett, LB Alexandrov, FX Real… - Nature, 2016 - nature.com
… ’ model of pancreatic cancer progression proposed by Real 19 more than a decade ago. …
Real, FXA A “catastrophic hypothesis” for pancreas cancer progression. Gastroenterology …

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

…, N Chatterjee, N Malats, X Wu, JD Figueroa, FX Real… - Nature …, 2010 - nature.com
We conducted a multi-stage, genome-wide association study of bladder cancer with a
primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of …

Anti-Hu antibodies in patients with small-cell lung cancer: association with complete response to therapy and improved survival.

…, WP Mason, R Rosell, JB Posner, FX Real - Journal of Clinical …, 1997 - ascopubs.org
PURPOSE Anti-Hu antibodies (HuAb) recognize antigens expressed by neurons and small-cell
lung cancer (SCLC). High titers of HuAb were initially reported in serum from patients …