[HTML][HTML] Efficient ReML inference in variance component mixed models using a Min-Max algorithm

F Laporte, A Charcosset… - PLoS computational …, 2022 - journals.plos.org
Since their introduction in the 50’s, variance component mixed models have been widely
used in many application fields. In this context, ReML estimation is by far the most popular …

Spinel oxides thin films for write-once optical recording with blue laser sources

…, I Pasquet, C Bonningue, F Laporte - Transactions of the …, 2002 - jstage.jst.go.jp
Non-stoichiometric spinel ferrite films are proposed in this work as write-once recording layers
for high density optical storage with blue laser sources. Two types of ferrite films has been …

Développement de méthodes statistiques pour l'identification de gènes d'intérêt en présence d'apparentement et de dominance, application à la génétique du maïs

F Laporte - 2018 - theses.hal.science
La détection de gènes est une étape importante dans la compréhension des effets de l'information
génétique d'un individu sur ses caractères phénotypiques. Durant mon doctorat, j'ai …

Modèles de classification non supervisée avec données manquantes non au hasard

F Laporte, C Biernacki, G Celeux, J Josse - JdS 2019-51e journées de …, 2019 - hal.science
La difficulté de prise en compte des données manquantes est souvent con-tournée en supposant
que leur occurrence est due au hasard. Dans cette communication, nous envisageons …

Estimating the effective sample size in association studies of quantitative traits

A Ziyatdinov, J Kim, D Prokopenko, F Privé, F Laporte… - G3, 2021 - academic.oup.com
The effective sample size (ESS) is a metric used to summarize in a single term the amount
of correlation in a sample. It is of particular interest when predicting the statistical power of …

[HTML][HTML] Comprehensive in silico and functional studies for classification of EPAS1/HIF2A genetic variants identified in patients with erythrocytosis

…, V Lesieur, A Rimbert, F Laporte… - …, 2023 - ncbi.nlm.nih.gov
Gain-of-function mutations in the EPAS1/HIF2A gene have been identified in patients with
hereditary erythrocytosis that can be associated with the development of paraganglioma, …

Model-based clustering with missing not at random data

A Sportisse, M Marbac, F Laporte, G Celeux… - arXiv preprint arXiv …, 2021 - arxiv.org
Model-based unsupervised learning, as any learning task, stalls as soon as missing data
occurs. This is even more true when the missing data are informative, or said missing not at …

Estimation of the relatedness coefficients from biallelic markers, application in plant mating designs

F Laporte, A Charcosset, T Mary‐Huard - Biometrics, 2017 - Wiley Online Library
The problem of inferring the relatedness distribution between two individuals from biallelic
marker data is considered. This problem can be cast as an estimation task in a mixture model: …

Rare coding variants in CTSO, a potential new actor of arterial remodeling, are associated to familial intracranial aneurysm

…, M Rio, S Bonnaud, P Lindenbaum, F Laporte… - medRxiv, 2023 - medrxiv.org
Background Intracranial aneurysm (IA) is a common cerebrovascular abnormality characterized
by localized dilation and wall thinning in intracranial arteries, that frequently leads to …

ChoruMM: a versatile multi-components mixed model for bacterial-GWAS

A Frouin, F Laporte, L Hafner, M Maury, ZR McCaw… - bioRxiv, 2023 - biorxiv.org
Genome-wide Association Studies (GWAS) have been central to studying the genetics of
complex human outcomes, and there is now tremendous interest in implementing GWAS-like …