Research focusing on the canonical adult myogenic progenitor, the skeletal muscle satellite
cell, is still an ever-growing field 46 years from their initial description. Recent publications …

Wnt is a family of signaling molecules involved in embryogenesis, adult tissue repair, and
cancer. They activate canonical and noncanonical Wnt signaling cascades in target cells. …

Adult skeletal muscle is endowed with regenerative potential through partially recapitulating
the embryonic developmental program. Upon acute injury or in pathological conditions, …

Satellite cells play a central role in mediating the growth and regeneration of skeletal muscle.
However, whether satellite cells are stem cells, committed progenitors, or dedifferentiated …

Efficient tissue regeneration is dependent on the coordinated responses of multiple cell types.
Here, we describe a new subpopulation of fibro/adipogenic progenitors (FAPs) resident in …

Satellite cells in skeletal muscle are a heterogeneous population of stem cells and committed
progenitors. We found that quiescent satellite stem cells expressed the Wnt receptor Fzd7 …

Satellite cells purified from adult skeletal muscle can participate extensively in muscle
regeneration and can also re-populate the satellite cell pool, suggesting that they have direct …

Adult tissue repair and regeneration require stem-progenitor cells that can self-renew and
generate differentiated progeny. Skeletal muscle regenerative capacity relies on muscle …

Mechanisms governing muscle satellite cell withdrawal from cell cycle to enter into quiescence
remain poorly understood. We studied the role of angiopoietin 1 (Ang1) and its receptor …

The mitogen-activated protein kinase p38-γ is highly expressed in skeletal muscle and is
associated with the dystrophin glycoprotein complex; however, its function remains unclear. …