Damage to vessels is one of the most common effects of therapeutic irradiation on normal
tissues. We undertook a study in patients treated with preoperative radiotherapy and …

About half of people with cancer are treated with radiation therapy; however, normal tissue
toxicity still remains a dose-limiting factor for this treatment. The skin response to ionizing …

Erythema was observed on the skin of the first patients treated with radiation therapy. It is in
particular to reduce this erythema, one feature of tissue inflammation, that prescribed dose to …

Ionizing radiation has historically been used to treat cancer by killing tumour cells, in particular
by inducing DNA damage. This view of radiotherapy (RT) as a simple cytotoxic agent has …

Background Radiotherapy (RT) for breast cancer presents a benefit in terms of reducing local
recurrence and deaths resulting from breast cancer but it can lead to secondary effects due …

Altered by ionising radiation, the vascular network is considered as a prime target to limit
normal tissue damage and improve tumour control in radiotherapy (RT). Irradiation damages …

The mechanisms underlying the development of glomerular lesions during aging are
largely unknown. It has been suggested that senescence might play a role, but the …

PURPOSE: To investigate the expression of a new fibrogenic cytokine the connective tissue
growth factor (CTGF) in intestinal radiation fibrosis and to characterize the mesenchymal cell …

This study was designed to determine whether dietary carnitine supplement could protect
cats from ketosis and improve carnitine and lipid metabolism in experimental feline hepatic …

Radiation proctitis is characterized by mucosal inflammation followed by adverse chronic
tissue remodeling and is associated with substantial morbidity and mortality. Mast cell …