User profiles for Fabrice N. Gravelat
Fabrice GravelatRI-MUHC Verified email at mail.mcgill.ca Cited by 1928 |
[HTML][HTML] Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System
FN Gravelat, A Beauvais, H Liu, MJ Lee… - PLoS …, 2013 - journals.plos.org
Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
[HTML][HTML] The fungal exopolysaccharide galactosaminogalactan mediates virulence by enhancing resistance to neutrophil extracellular traps
Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of
invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an …
invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an …
Role of Trehalose Biosynthesis in Aspergillus fumigatus Development, Stress Response, and Virulence
Aspergillus fumigatus is a pathogenic mold which causes invasive, often fatal, pulmonary
disease in immunocompromised individuals. Recently, proteins involved in the biosynthesis of …
disease in immunocompromised individuals. Recently, proteins involved in the biosynthesis of …
Aspergillus fumigatus MedA governs adherence, host cell interactions and virulence
FN Gravelat, DE Ejzykowicz, LY Chiang… - Cellular …, 2010 - Wiley Online Library
In medically important fungi, regulatory elements that control development and asexual
reproduction often govern the expression of virulence traits. We therefore cloned the Aspergillus …
reproduction often govern the expression of virulence traits. We therefore cloned the Aspergillus …
Transcriptional profiling identifies a role for BrlA in the response to nitrogen depletion and for StuA in the regulation of secondary metabolite clusters in Aspergillus …
K Twumasi-Boateng, Y Yu, D Chen, FN Gravelat… - Eukaryotic …, 2009 - Am Soc Microbiol
Conidiation (asexual sporulation) is a key developmental process in filamentous fungi. We
examined the gene regulatory roles of the Aspergillus fumigatus developmental transcription …
examined the gene regulatory roles of the Aspergillus fumigatus developmental transcription …
[HTML][HTML] Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell …
MJ Lee, FN Gravelat, RP Cerone, SD Baptista… - Journal of Biological …, 2014 - ASBMB
The cell wall of Aspergillus fumigatus contains two galactose-containing polysaccharides,
galactomannan and galactosaminogalactan, whose biosynthetic pathways are not well …
galactomannan and galactosaminogalactan, whose biosynthetic pathways are not well …
Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity
…, Y Sato, H Liu, M Lehoux, FN Gravelat… - Proceedings of the …, 2017 - National Acad Sciences
Galactosaminogalactan and Pel are cationic heteropolysaccharides produced by the opportunistic
pathogens Aspergillus fumigatus and Pseudomonas aeruginosa, respectively. These …
pathogens Aspergillus fumigatus and Pseudomonas aeruginosa, respectively. These …
Deacetylation of fungal exopolysaccharide mediates adhesion and biofilm formation
The mold Aspergillus fumigatus causes invasive infection in immunocompromised patients.
Recently, galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and …
Recently, galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and …
[HTML][HTML] Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus*♦
Aspergillus fumigatus is the most virulent species within the Aspergillus genus and causes
invasive infections with high mortality rates. The exopolysaccharide galactosaminogalactan (…
invasive infections with high mortality rates. The exopolysaccharide galactosaminogalactan (…
Aspergillus fumigatus Stimulates Leukocyte Adhesion Molecules and Cytokine Production by Endothelial Cells In Vitro and during Invasive Pulmonary Disease
LY Chiang, DC Sheppard, FN Gravelat… - Infection and …, 2008 - Am Soc Microbiol
Invasive aspergillosis is characterized by hyphal invasion of the blood vessels, which
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus fumigatus …
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus fumigatus …