[PDF][PDF] Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …
are suggestive of a selective advantage but may also be due to a random founder effect. We …
[HTML][HTML] Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study
…, LG Caller, SL Caddy, FA Khokhar… - The Lancet infectious …, 2020 - thelancet.com
Background The burden and influence of health-care associated severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …
Patterns of within-host genetic diversity in SARS-CoV-2
Monitoring the spread of SARS-CoV-2 and reconstructing transmission chains has become
a major public health focus for many governments around the world. The modest mutation …
a major public health focus for many governments around the world. The modest mutation …
A review on federated learning towards image processing
Nowadays, data privacy is an important consideration in machine learning. This paper
provides an overview of how Federated Learning can be used to improve data security and …
provides an overview of how Federated Learning can be used to improve data security and …
Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections
SARS-CoV-2 is notable both for its rapid spread, and for the heterogeneity of its patterns of
transmission, with multiple published incidences of superspreading behaviour. Here, we …
transmission, with multiple published incidences of superspreading behaviour. Here, we …
[HTML][HTML] Genomic characterisation of multidrug-resistant Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii in two intensive care units in Hanoi …
LW Roberts, FA Khokhar, NT Hoa, T Van Giang… - The Lancet …, 2022 - thelancet.com
Background Viet Nam has high rates of antimicrobial resistance (AMR) but little capacity for
genomic surveillance. This study used whole genome sequencing to examine the …
genomic surveillance. This study used whole genome sequencing to examine the …
[HTML][HTML] Genomic epidemiology of COVID-19 in care homes in the east of England
…, S Parmar, LG Caller, SL Caddy, FA Khokhar… - Elife, 2021 - elifesciences.org
COVID-19 poses a major challenge to care homes, as SARS-CoV-2 is readily transmitted and
causes disproportionately severe disease in older people. Here, 1,167 residents from 337 …
causes disproportionately severe disease in older people. Here, 1,167 residents from 337 …
A2B-COVID: a tool for rapidly evaluating potential SARS-CoV-2 transmission events
…, A Yakovleva, G Hall, FA Khokhar… - Molecular biology …, 2022 - academic.oup.com
Identifying linked cases of infection is a critical component of the public health response to
viral infectious diseases. In a clinical context, there is a need to make rapid assessments of …
viral infectious diseases. In a clinical context, there is a need to make rapid assessments of …
[HTML][HTML] Evidence of widespread endemic populations of highly multidrug resistant Klebsiella pneumoniae in hospital settings in Hanoi, Vietnam: a prospective cohort …
Background Patients with prolonged hospitalisation have a significant risk of carriage of and
subsequent infection with extended spectrum β-lactamase (ESBL)-producing and …
subsequent infection with extended spectrum β-lactamase (ESBL)-producing and …
[HTML][HTML] Antibiotic resistance determination using Enterococcus faecium whole-genome sequences: a diagnostic accuracy study using genotypic and phenotypic data
…, CA Yeats, KE Raven, C Ludden, FA Khokhar… - The Lancet …, 2024 - thelancet.com
Background DNA sequencing could become an alternative to in vitro antibiotic susceptibility
testing (AST) methods for determining antibiotic resistance by detecting genetic …
testing (AST) methods for determining antibiotic resistance by detecting genetic …