User profiles for Fan Gao
 | Fan GaoCaltech; MIT Verified email at caltech.edu Cited by 8893 |
Changes in passive mechanical properties of the gastrocnemius muscle at the muscle fascicle and joint levels in stroke survivors
Gao F, Grant TH, Roth EJ, Zhang LQ. Changes in passive mechanical properties of the
gastrocnemius muscle at the muscle fascicle and joint levels in stroke survivors. OBJECTIVES: …
gastrocnemius muscle at the muscle fascicle and joint levels in stroke survivors. OBJECTIVES: …
Single-cell transcriptomic analysis of Alzheimer's disease
Alzheimer’s disease is a pervasive neurodegenerative disorder, the molecular complexity of
which remains poorly understood. Here, we analysed 80,660 single-nucleus transcriptomes …
which remains poorly understood. Here, we analysed 80,660 single-nucleus transcriptomes …
[PDF][PDF] Temporal tracking of microglia activation in neurodegeneration at single-cell resolution
Microglia, the tissue-resident macrophages in the brain, are damage sensors that react to
nearly any perturbation, including neurodegenerative diseases such as Alzheimer's disease (…
nearly any perturbation, including neurodegenerative diseases such as Alzheimer's disease (…
Effects of SARS-CoV-2 variants on vaccine efficacy and response strategies
L Bian, F Gao, J Zhang, Q He, Q Mao, M Xu… - Expert review of …, 2021 - Taylor & Francis
Introduction As the global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic continues to spread, several variants have emerged. Variants B.1.1.7 and B.1.351 …
pandemic continues to spread, several variants have emerged. Variants B.1.1.7 and B.1.351 …
Impact of the Delta variant on vaccine efficacy and response strategies
L Bian, Q Gao, F Gao, Q Wang, Q He, X Wu… - Expert review of …, 2021 - Taylor & Francis
Introduction The Delta variant of SARS-CoV-2 has caused a new wave of the COVID-19
epidemic in many countries. It is the most infectious variant of SARS-CoV-2 to date, and its high …
epidemic in many countries. It is the most infectious variant of SARS-CoV-2 to date, and its high …
[PDF][PDF] Small molecular NIR-II fluorophores for cancer phototheranostics
Phototheranostics integrates deep-tissue imaging with phototherapy (containing photothermal
therapy and photodynamic therapy), holding great promise in early diagnosis and …
therapy and photodynamic therapy), holding great promise in early diagnosis and …
Gamma frequency entrainment attenuates amyloid load and modifies microglia
Abstract Changes in gamma oscillations (20–50 Hz) have been observed in several
neurological disorders. However, the relationship between gamma oscillations and cellular …
neurological disorders. However, the relationship between gamma oscillations and cellular …
Modular, efficient and constant-memory single-cell RNA-seq preprocessing
We describe a workflow for preprocessing of single-cell RNA-sequencing data that balances
efficiency and accuracy. Our workflow is based on the kallisto and bustools programs, and …
efficiency and accuracy. Our workflow is based on the kallisto and bustools programs, and …
[PDF][PDF] APOE4 causes widespread molecular and cellular alterations associated with Alzheimer's disease phenotypes in human iPSC-derived brain cell types
The apolipoprotein E4 (APOE4) variant is the single greatest genetic risk factor for sporadic
Alzheimer's disease (sAD). However, the cell-type-specific functions of APOE4 in relation to …
Alzheimer's disease (sAD). However, the cell-type-specific functions of APOE4 in relation to …
Efficacy, safety, and immunology of an inactivated alum-adjuvant enterovirus 71 vaccine in children in China: a multicentre, randomised, double-blind, placebo …
…, K Chu, QH Chen, YM Hu, X Wu, P Liu, LY Zhu, F Gao… - The Lancet, 2013 - thelancet.com
Background A vaccine for enterovirus 71 (EV71) is needed to address the high burden of
disease associated with infection. We assessed the efficacy, safety, immunogenicity, antibody …
disease associated with infection. We assessed the efficacy, safety, immunogenicity, antibody …