User profiles for Fanglei Zuo

Fanglei Zuo

Department of Medical Biochemistry and Biophysics, Karolinska Institutet
Verified email at ki.se
Cited by 1489

[HTML][HTML] Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant

F Zuo, H Abolhassani, L Du, A Piralla… - Nature …, 2022 - nature.com
The recent emergence of the Omicron variant has raised concerns on vaccine efficacy and
the urgent need to study more efficient vaccination strategies. Here we observed that an …

[HTML][HTML] Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant

…, H Maass, JC Sammartino, I Cassaniti, F Zuo… - BMC medicine, 2022 - Springer
Background The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In
November 2021, the Omicron variant was discovered and immediately classified as a variant of …

[PDF][PDF] Immunity to SARS-CoV-2 up to 15 months after infection

H Marcotte, A Piralla, F Zuo, L Du, I Cassaniti, H Wan… - IScience, 2022 - cell.com
Information concerning the longevity of immunity to SARS-CoV-2 following natural infection
may have considerable implications for durability of immunity induced by vaccines. Here, we …

[HTML][HTML] Design, structure and plasma binding of ancestral β-CoV scaffold antigens

…, K Schriever, R Sun, S Vlachiotis, F Zuo… - Nature …, 2023 - nature.com
We report the application of ancestral sequence reconstruction on coronavirus spike protein,
resulting in stable and highly soluble ancestral scaffold antigens (AnSAs). The AnSAs …

[HTML][HTML] Engineer probiotic bifidobacteria for food and biomedical applications-Current status and future prospective

F Zuo, S Chen, H Marcotte - Biotechnology Advances, 2020 - Elsevier
Bifidobacteria are members of the human gut microbiota and have shown to exert beneficial
effects on their host. Certain strains have a long history of safe and effective use as …

[HTML][HTML] Inherited IFNAR1 deficiency in a child with both critical COVID-19 pneumonia and multisystem inflammatory syndrome

…, L Du, M Aranda-Guillén, F Sardh, F Zuo… - Journal of clinical …, 2022 - Springer
Background Inborn errors of immunity (IEI) and autoantibodies to type I interferons (IFNs)
underlie critical COVID-19 pneumonia in at least 15% of the patients, while the causes of …

[HTML][HTML] Advancing mechanistic understanding and bioengineering of probiotic lactobacilli and bifidobacteria by genome editing

F Zuo, H Marcotte - Current Opinion in Biotechnology, 2021 - Elsevier
Fanglei Zuo thanks the Sven och Lilly Lawskis fond för naturvetenskaplig forskning (Grant
no. N2018-0030, P2019-0001), and KI Research Foundations Grants 2020-2021 (Grant no. FS…

Screening for potential novel probiotic Lactobacillus strains based on high dipeptidyl peptidase IV and α-glucosidase inhibitory activity

Z Zeng, J Luo, F Zuo, Y Zhang, H Ma, S Chen - Journal of Functional Foods, 2016 - Elsevier
Lactobacillus strains were screened for inhibition of dipeptidyl peptidase IV (DPP-IV) and α-glucosidase.
Cell-free excretory supernatants (CFS) and cell-free extracts (CFE) of 21 strains …

[HTML][HTML] Exopolysaccharide-Producing Bifidobacterium adolescentis Strains with Similar Adhesion Property Induce Differential Regulation of Inflammatory Immune …

R Yu, F Zuo, H Ma, S Chen - Nutrients, 2019 - mdpi.com
Intestinal bifidobacteria benefit human health by promoting and modulating the gut flora,
and boosting therapeutic efficiency for chronic metabolic diseases and cancer. Recently, …

Characterization and in vitro properties of potential probiotic Bifidobacterium strains isolated from breast-fed infant feces

F Zuo, R Yu, X Feng, L Chen, Z Zeng… - Annals of …, 2016 - Springer
Probiotics are live microorganisms that when administered in adequate amounts, confer
health benefits on the host. In this study, 13 strains of Bifidobacterium were isolated from three …